7 Papers
27 Citations
Jin Wang is an academic researcher from Third Military Medical University. The author has contributed to research in topics: Bone marrow & Cell cycle. The author has an hindex of 5, co-authored 5 publications.
Chat about Author
Papers
MicroRNA-144 regulates cancer cell proliferation and cell-cycle transition in acute lymphoblastic leukemia through the interaction of FMN2.
TL;DR: The functional roles of microRNA‐144 upregulation and downregulation in human acute lymphoblastic leukemia (ALL) are explored.
24
SRC3 expressed in bone marrow mesenchymal stem cells promotes the development of multiple myeloma.
TL;DR: The data showed that the expression of SRC3 in bone marrow mesenchymal stem cells (BM-MSCs) could promote cell proliferation and colony formation of MM cells through accelerating the transformation of the G1/S phase, no matter what kind of culture method was adopted.
11
Increased radiosensitivity and radiation-induced apoptosis in SRC-3 knockout mice
TL;DR: It is demonstrated that SRC-3 plays a role in radiation- induced apoptosis of BM hematopoietic cells, which highlights a potential therapeutic target for radiation-induced hematopsic injury.
7
Study on Aqueous Two-Phase Extraction of Teapolypheols from in Green Tea
TL;DR: In this article , the effects of ethanol/ ammonium sulfate aqueous two-phase extraction of tea polyphenols as the main research object, by changing the single factor method, the distribution coefficient, extraction rate, and yield of polyphenol in tea were studied.
Preclinical Evaluation of 9MW2821, a Site-Specific Monomethyl Auristatin E-based Antibody-Drug Conjugate for treatment of Nectin-4-expressing Cancers.
Wei Zhou,Peng Fang,Dong-An Yu,Meng You,Long Yin,Fei Mei,Zhenzhen Wang,Hui Xu,Xiaohong Xu,Jianjun Bi,Jin Wang,Lanping Ma,Xin Wang,Lin Chen,Yonglian Zhang,Xiaowei Cen,Xi Zhu,Liguang Lou,Datao Liu,Xiaoding Tan,Jinliang Yang,Tao Meng,Jingkang Shen +22 more
TL;DR: A second generation nectin-4-specific drug, 9MW2821, based on interchain disulfide drug conjugate technology was proposed in this article , which contained a site-specifically conjugated humanized antibody and the cytotoxic moiety monomethyl auristatin E.