Jimo Borjigin
University of Michigan
64 Papers
459 Citations
Jimo Borjigin is an academic researcher from University of Michigan. The author has contributed to research in topics: Melatonin & Pineal gland. The author has an hindex of 25, co-authored 59 publications. Previous affiliations of Jimo Borjigin include Carnegie Institution for Science & Oklahoma Medical Research Foundation.
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Papers
Transcriptional coactivator PGC-1α integrates the mammalian clock and energy metabolism
TL;DR: It is shown that PGC-1α (Ppargc1a), a transcriptional coactivator that regulates energy metabolism, is rhythmically expressed in the liver and skeletal muscle of mice and identified as a key component of the circadian oscillator that integrates the mammalian clock and energy metabolism.
668
Diurnal variation in mRNA encoding serotonin N-acetyltransferase in pineal gland
TL;DR: To identify proteins that regulate light–dark variations in pineal function, a subtractive hybridization technique based on the polymerase chain reaction (PCR) was used to isolate rat pineal gland messages that are differentially expressed by day and night.
282
Wilson disease in septuagenarian siblings: Raising the bar for diagnosis
TL;DR: It is suggested that WD must be considered at all ages in patients with hepatic disease, neurological disease, or psychiatric symptoms, as well as environmental and extragenic factors are pivotal determinants of disease phenotype.
209
Rhythmic Transcription: The Molecular Basis of Circadian Melatonin Synthesis
TL;DR: The molecular mechanisms involved in rhythmic synthesis of melatonin synthesis involve the CREM gene, which encodes transcription factors responsive to activation of the cAMP signalling pathway, and cAMP-responsive activator transcription factors CREB and ATF1 and the repressor ICER, which are highly conserved in the chick.
201
Circadian regulation of pineal gland rhythmicity
TL;DR: This review will focus on the central and pineal mechanisms in generation of mammalian pineal rhythmicity including melatonin production as well as local control of serotonin and melatonin rhythms.
157