Jill M. Dowen
Massachusetts Institute of Technology
24 Papers
634 Citations
Jill M. Dowen is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Cohesin & Gene. The author has an hindex of 9, co-authored 13 publications. Previous affiliations of Jill M. Dowen include University of North Carolina at Chapel Hill & University of California, San Diego.
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Papers
Widespread dynamic DNA methylation in response to biotic stress
Robert H. Dowen,Mattia Pelizzola,Robert J. Schmitz,Ryan Lister,Jill M. Dowen,Joseph R. Nery,Jack E. Dixon,Joseph R. Ecker +7 more
TL;DR: An unexpected role for DNA methylation is reported in regulation of the Arabidopsis thaliana immune system and changes within repetitive sequences or transposons can regulate neighboring genes in response to SA stress.
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Control of Cell Identity Genes Occurs in Insulated Neighborhoods in Mammalian Chromosomes
Jill M. Dowen,Zi Peng Fan,Denes Hnisz,Gang Ren,Brian J. Abraham,Abraham S. Weintraub,Jurian Schuijers,Tong Ihn Lee,Keji Zhao,Lyndon Nuoxi Zhang,Richard A. Young +10 more
- 01 Oct 2014
TL;DR: In this article, the authors used ESC cohesin ChIA-PET data to identify the local chromosomal structures at both active and repressed genes across the genome and reveal that super-enhancer-driven genes generally occur within chromosome structures that are formed by the looping of two interacting CTCF sites co-occupied by co-hesin.
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Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements
Jill M. Dowen,Steve Bilodeau,David A. Orlando,Michael R. Hübner,Brian J. Abraham,David L. Spector,Richard A. Young +6 more
TL;DR: In addition to their well-established functions in chromosome maintenance during mitosis, both cohesin and condensin II make important contributions to the functions of the key transcriptional regulatory elements during interphase.
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lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA.
Megan D. Schertzer,Keean C.A. Braceros,Joshua Starmer,Rachel E Cherney,David M Lee,Gabriela Salazar,Megan Justice,Steven R. Bischoff,Dale O. Cowley,Pablo Ariel,Mark J. Zylka,Jill M. Dowen,Terry Magnuson,J. Mauro Calabrese +13 more
TL;DR: It is proposed that CGIs that autonomously recruit PRCs interact with lncRNAs and their associated proteins through three-dimensional space to nucleate the spread of PRCs in lncRNA-targeted domains.
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Functional Studies and Homology Modeling of Msh2-Msh3 Predict that Mispair Recognition Involves DNA Bending and Strand Separation
TL;DR: Recognition of small insertion/deletion mispairs by Msh3 appears to require a greater degree of interactions with the DNA conformations induced by small insertion-deletions than with those induced by large insertion/ deletions that are intrinsically bent and strand separated.
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