Jiling Song
Washington University in St. Louis
6 Papers
37 Citations
Jiling Song is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Bioluminescence imaging & Biology. The author has an hindex of 5, co-authored 6 publications.
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Papers
Granzyme B and Perforin Are Important for Regulatory T Cell-Mediated Suppression of Tumor Clearance
Xuefang Cao,Sheng F. Cai,Todd A. Fehniger,Jiling Song,Lynne Collins,David Piwnica-Worms,Timothy J. Ley +6 more
TL;DR: It is shown here that granzyme B-deficient mice clear both allogeneic and syngeneic tumor cell lines more efficiently than do wild-type (WT) mice and Granzyme B and perforin are relevant for Treg cell-mediated suppression of tumor clearance in vivo.
958
Imaging 26S proteasome activity and inhibition in living mice
TL;DR: The development of a ubiquitin-luciferase reporter for bioluminescence imaging enables repetitive tissue-specific analysis of 26S proteasome activity in vivo and should facilitate development and validation of proteasomesome inhibitors in mouse models, as well as investigations of the ubiquitIn-proteasome pathway in disease pathogenesis.
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Intracellular water specific MR of microbead-adherent cells: HeLa cell intracellular water diffusion.
L. Zhao,A. L. Sukstanskii,Christopher D. Kroenke,Jiling Song,David Piwnica-Worms,Joseph J. H. Ackerman,Jeffrey J. Neil +6 more
TL;DR: Intracellular water MR diffusion‐signal attenuation at various diffusion times was well described and the cell radius inferred from modeling the incoherent displacement of intracellular water by a truncated Gaussian distribution of ADCs was confirmed by independent optical microscopy measures.
38
Intracellular water-specific MR of microbead-adherent cells: The HeLa cell intracellular water exchange lifetime
L. Zhao,L. Zhao,Christopher D. Kroenke,Jiling Song,David Piwnica-Worms,Joseph J. H. Ackerman,Jeffrey J. Neil +6 more
TL;DR: This work describes how high‐velocity perfusion of microbead‐adherent cells results in short apparent 1H MR longitudinal and transverse relaxation times for the extracellular water in a thin slice selected orthogonal to the direction of flow, and exploits the kinetics of water exchange from the intracellular to extacellular spaces of HeLa cells.