175 Papers
1.3K Citations
Jie Yao is an academic researcher from Los Angeles Biomedical Research Institute. The author has contributed to research in topics: Genome-wide association study & Biology. The author has an hindex of 43, co-authored 137 publications. Previous affiliations of Jie Yao include University of California, Los Angeles & Boston University.
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Papers
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.
Evangelos Evangelou,Evangelos Evangelou,Helen R. Warren,Helen R. Warren,David Mosen-Ansorena,Borbala Mifsud,Raha Pazoki,He Gao,Georgios Ntritsos,Niki Dimou,Claudia P. Cabrera,Claudia P. Cabrera,Ibrahim Karaman,Fu Liang Ng,Marina Evangelou,K. Witkowska,Evan Tzanis,Jacklyn N. Hellwege,Ayush Giri,Digna R. Velez Edwards,Yan V. Sun,Kelly Cho,Kelly Cho,J. Michael Gaziano,J. Michael Gaziano,Peter W.F. Wilson,Philip S. Tsao,Csaba P. Kovesdy,Tõnu Esko,Tõnu Esko,Reedik Mägi,Lili Milani,Peter Almgren,Thibaud Boutin,Stéphanie Debette,Jun Ding,Franco Giulianini,Elizabeth G. Holliday,Anne U. Jackson,Ruifang Li-Gao,Wei-Yu Lin,Jian'an Luan,Massimo Mangino,Massimo Mangino,Christopher Oldmeadow,Bram P. Prins,Yong Qian,Muralidharan Sargurupremraj,Nabi Shah,Nabi Shah,Praveen Surendran,Sébastien Thériault,Sébastien Thériault,Niek Verweij,Niek Verweij,Niek Verweij,Sara M. Willems,Jing Hua Zhao,Philippe Amouyel,John M. C. Connell,Renée de Mutsert,Alex S. F. Doney,Martin Farrall,Martin Farrall,Cristina Menni,Andrew D. Morris,Raymond Noordam,Guillaume Paré,Neil Poulter,Denis C. Shields,Alice Stanton,Simon Thom,Gonçalo R. Abecasis,Najaf Amin,Dan E. Arking,Kristin L. Ayers,Kristin L. Ayers,Caterina Barbieri,Chiara Batini,Joshua C. Bis,Tineka Blake,Murielle Bochud,Michael Boehnke,Eric Boerwinkle,Dorret I. Boomsma,Erwin P. Bottinger,Peter S. Braund,Peter S. Braund,Marco Brumat,Archie Campbell,Harry Campbell,Aravinda Chakravarti,John C. Chambers,Ganesh Chauhan,Marina Ciullo,Massimiliano Cocca,Francis S. Collins,Heather J. Cordell,Gail Davies,Martin H. de Borst,Eco J. C. de Geus,Ian J. Deary,Joris Deelen,Fabiola Del Greco M,Cumhur Y Demirkale,Marcus Dörr,Georg Ehret,Georg Ehret,Roberto Elosua,Stefan Enroth,A. Mesut Erzurumluoglu,Teresa Ferreira,Mattias Frånberg,Mattias Frånberg,Oscar H. Franco,Ilaria Gandin,Paolo Gasparini,Vilmantas Giedraitis,Christian Gieger,Giorgia Girotto,Anuj Goel,Anuj Goel,Alan J. Gow,Alan J. Gow,Vilmundur Gudnason,Xiuqing Guo,Ulf Gyllensten,Anders Hamsten,Tamara B. Harris,Sarah E. Harris,Catharina A. Hartman,Aki S. Havulinna,Aki S. Havulinna,Andrew A. Hicks,Edith Hofer,Albert Hofman,Albert Hofman,Jouke-Jan Hottenga,Jennifer E. Huffman,Jennifer E. Huffman,Shih-Jen Hwang,Erik Ingelsson,Erik Ingelsson,Alan James,Alan James,Rick Jansen,Marjo-Riitta Järvelin,Roby Joehanes,Åsa Johansson,Andrew D. Johnson,Peter K. Joshi,Pekka Jousilahti,J. Wouter Jukema,Antti Jula,Mika Kähönen,Sekar Kathiresan,Sekar Kathiresan,Sekar Kathiresan,Bernard Keavney,Bernard Keavney,Kay-Tee Khaw,Paul Knekt,Joanne Knight,Ivana Kolcic,Jaspal S. Kooner,Seppo Koskinen,Kati Kristiansson,Zoltán Kutalik,Zoltán Kutalik,Maris Laan,Marty Larson,Lenore J. Launer,Benjamin Lehne,Terho Lehtimäki,David C. Liewald,Li Lin,Lars Lind,Cecilia M. Lindgren,Cecilia M. Lindgren,Cecilia M. Lindgren,Yongmei Liu,Ruth J. F. Loos,Ruth J. F. Loos,Lorna M. Lopez,Lorna M. Lopez,Lorna M. Lopez,Yingchang Lu,Leo-Pekka Lyytikäinen,Anubha Mahajan,Chrysovalanto Mamasoula,Jaume Marrugat,Jonathan Marten,Yuri Milaneschi,Anna Morgan,Andrew P. Morris,Andrew P. Morris,Alanna C. Morrison,Peter J. Munson,Mike A. Nalls,Priyanka Nandakumar,Christopher P. Nelson,Christopher P. Nelson,Teemu J. Niiranen,Teemu J. Niiranen,Ilja M. Nolte,Teresa Nutile,Albertine J. Oldehinkel,Ben A. Oostra,Paul F. O'Reilly,Elin Org,Sandosh Padmanabhan,Sandosh Padmanabhan,Walter Palmas,Aarno Palotie,Aarno Palotie,Aarno Palotie,Alison Pattie,Brenda W.J.H. Penninx,Markus Perola,Markus Perola,Markus Perola,Annette Peters,Ozren Polasek,Peter P. Pramstaller,Quang Tri Nguyen,Olli T. Raitakari,Olli T. Raitakari,Meixia Ren,Rainer Rettig,Kenneth Rice,Paul M. Ridker,Paul M. Ridker,Janina S. Ried,Harriëtte Riese,Samuli Ripatti,Antonietta Robino,Lynda M. Rose,Jerome I. Rotter,Igor Rudan,Daniela Ruggiero,Yasaman Saba,Cinzia Sala,Veikko Salomaa,Nilesh J. Samani,Nilesh J. Samani,Antti-Pekka Sarin,Reinhold Schmidt,Helena Schmidt,Nick Shrine,David S. Siscovick,Albert V. Smith,Harold Snieder,Siim Sõber,Rossella Sorice,John M. Starr,David J. Stott,David P. Strachan,Rona J. Strawbridge,Johan Sundström,Morris A. Swertz,Kent D. Taylor,Alexander Teumer,Martin D. Tobin,Maciej Tomaszewski,Maciej Tomaszewski,Daniela Toniolo,Michela Traglia,Stella Trompet,Jaakko Tuomilehto,Christophe Tzourio,André G. Uitterlinden,Ahmad Vaez,Ahmad Vaez,Peter J. van der Most,Cornelia M. van Duijn,Anne-Claire Vergnaud,Germaine C. Verwoert,Veronique Vitart,Uwe Völker,Peter Vollenweider,Dragana Vuckovic,Dragana Vuckovic,Hugh Watkins,Hugh Watkins,Sarah H. Wild,Gonneke Willemsen,James F. Wilson,James F. Wilson,Alan F. Wright,Jie Yao,Tatijana Zemunik,Weihua Zhang,Weihua Zhang,John Attia,Adam S. Butterworth,Adam S. Butterworth,Daniel I. Chasman,Daniel I. Chasman,David Conen,David Conen,Francesco Cucca,Francesco Cucca,John Danesh,John Danesh,Caroline Hayward,Joanna M. M. Howson,Markku Laakso,Edward G. Lakatta,Claudia Langenberg,Olle Melander,Dennis O. Mook-Kanamori,Colin N. A. Palmer,Lorenz Risch,Robert A. Scott,Rodney J. Scott,Peter S. Sever,Tim D. Spector,Pim van der Harst,Nicholas J. Wareham,Eleftheria Zeggini,Daniel Levy,Patricia B. Munroe,Patricia B. Munroe,Christopher Newton-Cheh,Christopher Newton-Cheh,Morris J. Brown,Morris J. Brown,Andres Metspalu,Adriana M. Hung,Christopher J. O'Donnell,Todd L. Edwards,Bruce M. Psaty,Bruce M. Psaty,Ioanna Tzoulaki,Ioanna Tzoulaki,Michael R. Barnes,Michael R. Barnes,Louise V. Wain,Louise V. Wain,Paul Elliott,Mark J. Caulfield,Mark J. Caulfield +341 more
TL;DR: In this article, the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry was conducted.
Multi-Ethnic Genome-wide Association Study for Atrial Fibrillation
Carolina Roselli,Mark Chaffin,Lu-Chen Weng,Lu-Chen Weng,Stefanie Aeschbacher,Gustav Ahlberg,Christine M. Albert,Peter Almgren,Alvaro Alonso,Christopher D. Anderson,Christopher D. Anderson,Krishna G. Aragam,Krishna G. Aragam,Dan E. Arking,John Barnard,Traci M. Bartz,Emelia J. Benjamin,Emelia J. Benjamin,Nathan A. Bihlmeyer,Joshua C. Bis,Heather L. Bloom,Eric Boerwinkle,Erwin B. Bottinger,Jennifer A. Brody,Hugh Calkins,Archie Campbell,Thomas P. Cappola,John F. Carlquist,John F. Carlquist,Daniel I. Chasman,Daniel I. Chasman,Lin Y. Chen,Yii-Der Ida Chen,Eue Keun Choi,Seung Hoan Choi,Ingrid E. Christophersen,Ingrid E. Christophersen,Ingrid E. Christophersen,Mina K. Chung,John W. Cole,John W. Cole,David Conen,David Conen,James P. Cook,Harry J.G.M. Crijns,Michael J. Cutler,Scott M. Damrauer,Scott M. Damrauer,Brian R. Daniels,Dawood Darbar,Graciela Delgado,Joshua C. Denny,Martin Dichgans,Martin Dichgans,Marcus Dörr,Elton A. M. P. Dudink,Samuel C. Dudley,Nada Esa,Tõnu Esko,Tõnu Esko,Markku Eskola,Diane Fatkin,Diane Fatkin,Diane Fatkin,Stephan B. Felix,Ian Ford,Oscar H. Franco,Bastiaan Geelhoed,Raji P. Grewal,Raji P. Grewal,Vilmundur Gudnason,Xiuqing Guo,Namrata Gupta,Stefan Gustafsson,Rebecca Gutmann,Anders Hamsten,Tamara B. Harris,Caroline Hayward,Susan R. Heckbert,Susan R. Heckbert,Jussi Hernesniemi,Lynne J. Hocking,Albert Hofman,Andrea R. V. R. Horimoto,Jie Huang,Paul L. Huang,Jennifer E. Huffman,Erik Ingelsson,Erik Ingelsson,Esra Gucuk Ipek,Kaoru Ito,Jordi Jimenez-Conde,Jordi Jimenez-Conde,Renee Johnson,J. Wouter Jukema,Stefan Kääb,Mika Kähönen,Yoichiro Kamatani,John P. Kane,Adnan Kastrati,Sekar Kathiresan,Sekar Kathiresan,Petra Katschnig-Winter,Maryam Kavousi,Thorsten Kessler,Bas L.J.H. Kietselaer,Paulus Kirchhof,Marcus E. Kleber,Stacey Knight,Stacey Knight,José Eduardo Krieger,Michiaki Kubo,Lenore J. Launer,Jari Laurikka,Terho Lehtimäki,Kirsten Leineweber,Rozenn N. Lemaitre,Man Li,Man Li,Hong Euy Lim,Henry J. Lin,Honghuang Lin,Honghuang Lin,Lars Lind,Cecilia M. Lindgren,Marja-Liisa Lokki,Barry London,Ruth J. F. Loos,Siew-Kee Low,Yingchang Lu,Leo-Pekka Lyytikäinen,Peter W. Macfarlane,Patrik K. E. Magnusson,Anubha Mahajan,Rainer Malik,Alfredo José Mansur,Gregory M. Marcus,Lauren Margolin,Kenneth B. Margulies,Winfried März,Winfried März,David D. McManus,Olle Melander,Sanghamitra Mohanty,Jay A. Montgomery,Michael Morley,Andrew P. Morris,Martina Müller-Nurasyid,Andrea Natale,Saman Nazarian,Benjamin Neumann,Christopher Newton-Cheh,Christopher Newton-Cheh,Maartje N. Niemeijer,Kjell Nikus,Peter M. Nilsson,Raymond Noordam,Heidi Oellers,Morten S. Olesen,Marju Orho-Melander,Sandosh Padmanabhan,Hui Nam Pak,Guillaume Paré,Guillaume Paré,Nancy L. Pedersen,Joanna Pera,Alexandre C. Pereira,David J. Porteous,Bruce M. Psaty,Bruce M. Psaty,Sara L. Pulit,Sara L. Pulit,Sara L. Pulit,Clive R. Pullinger,Daniel J. Rader,Lena Refsgaard,Marta Ribasés,Marta Ribasés,Paul M. Ridker,Michiel Rienstra,Lorenz Risch,Dan M. Roden,Jonathan Rosand,Jonathan Rosand,Michael A. Rosenberg,Michael A. Rosenberg,Natalia S. Rost,Natalia S. Rost,Jerome I. Rotter,Samir Saba,Roopinder K. Sandhu,Renate B. Schnabel,Katharina Schramm,Heribert Schunkert,Claudia Schurman,Stuart A. Scott,Ilkka Seppälä,Christian M. Shaffer,Svati H. Shah,Alaa Shalaby,Alaa Shalaby,Jaemin Shim,M. Benjamin Shoemaker,Joylene E. Siland,Juha Sinisalo,Moritz F. Sinner,Agnieszka Slowik,Albert V. Smith,Blair H. Smith,J. Gustav Smith,J. Gustav Smith,Jonathan D. Smith,Nicholas L. Smith,Nicholas L. Smith,Elsayed Z. Soliman,Nona Sotoodehnia,Bruno H. Stricker,Albert Y. Sun,Han Sun,Jesper Hastrup Svendsen,Toshihiro Tanaka,Kahraman Tanriverdi,Kent D. Taylor,Maris Teder-Laving,Alexander Teumer,Sébastien Thériault,Sébastien Thériault,Stella Trompet,Nathan R. Tucker,Nathan R. Tucker,Arnljot Tveit,Arnljot Tveit,André G. Uitterlinden,Pim van der Harst,Isabelle C. Van Gelder,David R. Van Wagoner,Niek Verweij,Efthymia Vlachopoulou,Uwe Völker,Biqi Wang,Peter Weeke,Peter Weeke,Bob Weijs,Raul Weiss,Stefan Weiss,Quinn S. Wells,Kerri L. Wiggins,Jorge A. Wong,Daniel Woo,Bradford B. Worrall,Pil Sung Yang,Jie Yao,Zachary T. Yoneda,Tanja Zeller,Lingyao Zeng,Steven A. Lubitz,Steven A. Lubitz,Kathryn L. Lunetta,Kathryn L. Lunetta,Patrick T. Ellinor,Patrick T. Ellinor +260 more
TL;DR: This large, multi-ethnic genome-wide association study identifies 97 loci significantly associated with atrial fibrillation that are enriched for genes involved in cardiac development, electrophysiology, structure and contractile function.
Predictors of mortality in hospitalized COVID-19 patients: A systematic review and meta-analysis.
Wenjie Tian,Wenjie Tian,Wanlin Jiang,Jie Yao,Jie Yao,Christopher J. Nicholson,Rebecca H. Li,Haakon H. Sigurslid,Luke Wooster,Jerome I. Rotter,Jerome I. Rotter,Xiuqing Guo,Xiuqing Guo,Rajeev Malhotra +13 more
TL;DR: Individuals with underlying cardiometabolic disease and that present with evidence for acute inflammation and end‐organ damage are at higher risk of mortality due to COVID‐19 infection and should be managed with greater intensity.
637
The trans-ancestral genomic architecture of glycemic traits
Ji Chen,Ji Chen,Cassandra N. Spracklen,Cassandra N. Spracklen,Gaëlle Marenne,Gaëlle Marenne,Arushi Varshney,Laura J Corbin,Jian'an Luan,Sara M. Willems,Ying Wu,Xiaoshuai Zhang,Xiaoshuai Zhang,Momoko Horikoshi,Thibaud S. Boutin,Reedik Mägi,Johannes Waage,Ruifang Li-Gao,Kei Hang Katie Chan,Kei Hang Katie Chan,Jie Yao,Mila Desi Anasanti,Audrey Y. Chu,Annique Claringbould,Jani Heikkinen,Jaeyoung Hong,Jouke-Jan Hottenga,Jouke-Jan Hottenga,Shaofeng Huo,Marika Kaakinen,Marika Kaakinen,Tin Louie,Winfried März,Winfried März,Winfried März,Hortensia Moreno-Macías,Anne Ndungu,Sarah C. Nelson,Ilja M. Nolte,Kari E. North,Chelsea K. Raulerson,Debashree Ray,Rebecca Rohde,Denis Rybin,Claudia Schurmann,Claudia Schurmann,Xueling Sim,Xueling Sim,Lorraine Southam,Isobel D. Stewart,Carol A. Wang,Yujie Wang,Peitao Wu,Weihua Zhang,Weihua Zhang,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Emil V. R. Appel,Lawrence F. Bielak,Jennifer A. Brody,Noël P. Burtt,Claudia P. Cabrera,Brian E. Cade,Brian E. Cade,Jin Fang Chai,Xiaoran Chai,Li-Ching Chang,Chien-Hsiun Chen,Brian H. Chen,Kumaraswamy Naidu Chitrala,Yen-Feng Chiu,Hugoline G. de Haan,Graciela E. Delgado,Ayse Demirkan,Ayse Demirkan,Qing Duan,Jorgen Engmann,Segun Fatumo,Javier Gayán,Franco Giulianini,Jung Ho Gong,Stefan Gustafsson,Yang Hai,Fernando Pires Hartwig,Fernando Pires Hartwig,Jing He,Yoriko Heianza,Tao Huang,Alicia Huerta-Chagoya,Mi Yeong Hwang,Richard A. Jensen,Takahisa Kawaguchi,Katherine A. Kentistou,Young-Jin Kim,Marcus E. Kleber,Ishminder K. Kooner,Shuiqing Lai,Leslie A. Lange,Carl D. Langefeld,Marie Lauzon,Man Li,Symen Ligthart,Jun Liu,Jun Liu,Marie Loh,Marie Loh,Jirong Long,Valeriya Lyssenko,Valeriya Lyssenko,Massimo Mangino,Massimo Mangino,Carola Marzi,May E. Montasser,Abhishek Nag,Masahiro Nakatochi,Damia Noce,Raymond Noordam,Giorgio Pistis,Michael Preuss,Laura M. Raffield,Laura J. Rasmussen-Torvik,Stephen S. Rich,Neil R. Robertson,Rico Rueedi,Rico Rueedi,Kathleen A. Ryan,Serena Sanna,Richa Saxena,Richa Saxena,Katharina E. Schraut,Bengt Sennblad,Kazuya Setoh,Albert V. Smith,Thomas Sparsø,Rona J. Strawbridge,Rona J. Strawbridge,Fumihiko Takeuchi,Jingyi Tan,Stella Trompet,Erik B. van den Akker,Erik B. van den Akker,Peter J. van der Most,Niek Verweij,Mandy Vogel,Heming Wang,Heming Wang,Chaolong Wang,Chaolong Wang,Nan Wang,Helen R. Warren,Wanqing Wen,Tom Wilsgaard,Andrew Wong,Andrew R. Wood,Tian Xie,Mohammad Hadi Zafarmand,Jing Hua Zhao,Wei Zhao,N. Amin,N. Amin,Zorayr Arzumanyan,Arne Astrup,Stephan J. L. Bakker,Damiano Baldassarre,Marian Beekman,Richard N. Bergman,Alain G. Bertoni,Matthias Blüher,Lori L. Bonnycastle,Stefan R. Bornstein,Donald W. Bowden,Qiuyin Cai,Archie Campbell,Archie Campbell,Harry Campbell,Yi-Cheng Chang,Yi-Cheng Chang,Eco J. C. de Geus,Eco J. C. de Geus,Abbas Dehghan,Shufa Du,Gudny Eiriksdottir,Aliki-Eleni Farmaki,Aliki-Eleni Farmaki,Mattias Frånberg,Christian Fuchsberger,Yu-Tang Gao,Anette P. Gjesing,Anuj Goel,Sohee Han,Catharina A. Hartman,Christian Herder,Andrew A. Hicks,Chang-Hsun Hsieh,Chang-Hsun Hsieh,Willa A. Hsueh,Sahoko Ichihara,Michiya Igase,M. Arfan Ikram,W. Craig Johnson,Marit E. Jørgensen,Marit E. Jørgensen,Peter K. Joshi,Rita R. Kalyani,Fouad Kandeel,Tomohiro Katsuya,Chiea Chuen Khor,Wieland Kiess,Ivana Kolcic,Teemu Kuulasmaa,Johanna Kuusisto,Kristi Läll,Kelvin Lam,Debbie A Lawlor,Nanette R. Lee,Rozenn N. Lemaitre,Honglan Li,Shih-Yi Lin,Jaana Lindström,Allan Linneberg,Allan Linneberg,Jianjun Liu,Jianjun Liu,Carlos Lorenzo,Tatsuaki Matsubara,Fumihiko Matsuda,Geltrude Mingrone,Simon P. Mooijaart,Sanghoon Moon,Toru Nabika,Girish N. Nadkarni,Jerry L. Nadler,Mari Nelis,Matt J. Neville,Jill M. Norris,Yasumasa Ohyagi,Annette Peters,Patricia A. Peyser,Ozren Polasek,Qibin Qi,Dennis Raven,Dermot F. Reilly,Alexander P. Reiner,Fernando Rivideneira,Kathryn Roll,Igor Rudan,Charumathi Sabanayagam,Kevin Sandow,Naveed Sattar,Annette Schürmann,Shi Jinxiu,Heather M. Stringham,Kent D. Taylor,Tanya M. Teslovich,Betina H. Thuesen,Paul R. H. J. Timmers,Elena Tremoli,Michael Y. Tsai,André G. Uitterlinden,Rob M. van Dam,Rob M. van Dam,Rob M. van Dam,Diana van Heemst,Astrid van Hylckama Vlieg,Jana V. van Vliet-Ostaptchouk,Jagadish Vangipurapu,Henrik Vestergaard,Tao Wang,Ko Willems van Dijk,Tatijana Zemunik,Gonçalo R. Abecasis,Linda S. Adair,Carlos A. Aguilar-Salinas,Marta E. Alarcón-Riquelme,Marta E. Alarcón-Riquelme,Ping An,M. Larissa Avilés-Santa,Diane M. Becker,Lawrence J. Beilin,Sven Bergmann,Sven Bergmann,Sven Bergmann,Hans Bisgaard,Corri Black,Michael Boehnke,Eric Boerwinkle,Eric Boerwinkle,Bernhard O. Böhm,Bernhard O. Böhm,Klaus Bønnelykke,D.I. Boomsma,D.I. Boomsma,Erwin P. Bottinger,Erwin P. Bottinger,Thomas A. Buchanan,Mickaël Canouil,Mickaël Canouil,Mark J. Caulfield,John C. Chambers,Daniel I. Chasman,Daniel I. Chasman,Yii-Der Ida Chen,Ching-Yu Cheng,Francis S. Collins,Adolfo Correa,Francesco Cucca,H. Janaka de Silva,George Dedoussis,Sölve Elmståhl,Michele K. Evans,Ele Ferrannini,Luigi Ferrucci,Jose C. Florez,Jose C. Florez,Paul W. Franks,Paul W. Franks,Timothy M. Frayling,Philippe Froguel,Philippe Froguel,Philippe Froguel,Bruna Gigante,Mark O. Goodarzi,Penny Gordon-Larsen,Harald Grallert,Niels Grarup,Sameline Grimsgaard,Leif Groop,Leif Groop,Vilmundur Gudnason,Xiuqing Guo,Anders Hamsten,Torben Hansen,Caroline Hayward,Susan R. Heckbert,Bernardo L. Horta,Wei Huang,Erik Ingelsson,Pankow S. James,Marjo-Ritta Jarvelin,Jost B. Jonas,Jost B. Jonas,J. Wouter Jukema,Pontiano Kaleebu,Robert C. Kaplan,Robert C. Kaplan,Sharon L.R. Kardia,Norihiro Kato,Sirkka Keinänen-Kiukaanniemi,Sirkka Keinänen-Kiukaanniemi,Bong-Jo Kim,Mika Kivimäki,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Jaspal S. Kooner,Antje Körner,Peter Kovacs,Diana Kuh,Meena Kumari,Zoltán Kutalik,Zoltán Kutalik,Markku Laakso,Timo A. Lakka,Lenore J. Launer,Karin Leander,Huaixing Li,Xu Lin,Lars Lind,Cecilia M. Lindgren,Simin Liu,Ruth J. F. Loos,Patrik K. E. Magnusson,Anubha Mahajan,Anubha Mahajan,Andres Metspalu,Dennis O. Mook-Kanamori,Trevor A. Mori,Patricia B. Munroe,Inger Njølstad,Jeffrey R. O'Connell,Albertine J. Oldehinkel,Ken K. Ong,Sandosh Padmanabhan,Colin N. A. Palmer,Nicholette D. Palmer,Oluf Pedersen,Craig E. Pennell,David J. Porteous,David J. Porteous,Peter P. Pramstaller,Michael A. Province,Bruce M. Psaty,Lu Qi,Leslie J. Raffel,Rainer Rauramaa,Susan Redline,Susan Redline,Paul M. Ridker,Frits R. Rosendaal,Timo Saaristo,Manjinder S. Sandhu,Jouko Saramies,Neil Schneiderman,Peter E. H. Schwarz,Peter E. H. Schwarz,Laura J. Scott,Elizabeth Selvin,Peter S. Sever,Xiao-Ou Shu,P. Eline Slagboom,Kerrin S. Small,Blair H. Smith,Harold Snieder,Tamar Sofer,Tamar Sofer,Thorkild I. A. Sørensen,Tim D. Spector,Alice Stanton,Claire J. Steves,Claire J. Steves,Michael Stumvoll,Liang Sun,Yasuharu Tabara,E. Shyong Tai,E. Shyong Tai,Nicholas J. Timpson,Anke Tönjes,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,Teresa Tusie,Matti Uusitupa,Pim van der Harst,Cornelia M. van Duijn,Cornelia M. van Duijn,Veronique Vitart,Peter Vollenweider,Tanja G. M. Vrijkotte,Lynne E. Wagenknecht,Mark Walker,Ya X. Wang,Nicholas J. Wareham,Richard M. Watanabe,Hugh Watkins,Wen B. Wei,Ananda R. Wickremasinghe,Gonneke Willemsen,Gonneke Willemsen,James F. Wilson,Tien Yin Wong,Jer-Yuarn Wu,Anny H. Xiang,Lisa R. Yanek,Loic Yengo,Mitsuhiro Yokota,Eleftheria Zeggini,Eleftheria Zeggini,Wei Zheng,Alan B. Zonderman,Jerome I. Rotter,Anna L. Gloyn,Mark I. McCarthy,Josée Dupuis,James B. Meigs,James B. Meigs,Robert A. Scott,Inga Prokopenko,Inga Prokopenko,Aaron Leong,Ching-Ti Liu,Stephen C. J. Parker,Karen L. Mohlke,Claudia Langenberg,Eleanor Wheeler,Eleanor Wheeler,Andrew P. Morris,Inês Barroso,Inês Barroso,Inês Barroso +478 more
TL;DR: This paper aggregated genome-wide association studies comprising up to 281,416 individuals without diabetes (30% non-European ancestry) for whom fasting glucose, 2-h glucose after an oral glucose challenge, glycated hemoglobin and fasting insulin data were available.
633
A saturated map of common genetic variants associated with human height
Loic Yengo,Sailaja Vedantam,Eirini Marouli,Julia Sidorenko,Eric Bartell,Saori Sakaue,Marielisa Graff,Anders U. Eliasen,Yunxuan Jiang,Sridharan Raghavan,Jenkai Miao,Joshua Daniel Arias,Ronen E. Mukamel,Cassandra N. Spracklen,Xianyong Yin,Shyh-Huei Chen,Teresa Ferreira,JI Yingjie,Kreete Lüll,Kuang Lin,Deborah E. Malden,Carolina Medina-Gomez,Moara Machado,Amy Moore,Sina Rüeger,Tarunveer S. Ahluwalia,Masato Akiyama,Matthew A. Allison,Marcus Alvarez,Mette K. Andersen,Alireza Ani,Vivek Appadurai,Liubov Arbeeva,Seema Bhaskar,Lawrence F. Bielak,Sailalitha Bollepalli,Lori L. Bonnycastle,Jette Bork-Jensen,Jonathan P. Bradfield,Yuki Bradford,Peter S. Braund,Jennifer A. Brody,Kristoffer Sølvsten Burgdorf,Brian E. Cade,Hui Cai,Qiuyin Cai,Archie Campbell,Marisa Cañadas-Garre,Eulalia Catamo,Jin-Fang Chai,Xiaoran Chai,Li Chang,Yipeng Chang,Chien-Hsiun Chen,Alessandra Chesi,Seung Hoan Choi,Ren-Hua Chung,Massimiliano Cocca,Maria Pina Concas,Christian Couture,Gabriel Cuellar-Partida,Rebecca D Danning,E. Warwick Daw,Frauke Degenhard,Graciela E. Delgado,Alessandro P Delitala,Ayse Demirkan,Xuan Deng,Poornima Devineni,Alexander Dietl,Maria Dimitriou,Latchezar Dimitrov,Rajkumar Dorajoo,Arif B. Ekici,Jorgen Engmann,Zammy Fairhurst-Hunter,Aliki-Eleni Farmaki,Jessica D. Faul,Juan Carlos Fernández-López,Lukas Forer,Margherita Francescatto,Sandra Freitag-Wolf,Christian Fuchsberger,Tessel E. Galesloot,Yan Gao,Zishan Gao,Frank Geller,Olga Giannakopoulou,Franco Giulianini,Anette P. Gjesing,Anuj Goel,Scott D. Gordon,Mathias Gorski,Sarah E. Graham,Jakob Grove,Xiuqing Guo,Stefan Gustafsson,Jeffrey Haessler,Thomas Hansen,Aki S. Havulinna,Simon Haworth,Jiang He,Nancy L. Heard-Costa,Prashantha Hebbar,George Hindy,Yuk-Lam Ho,Edith Hofer,Elizabeth G. Holliday,Katrin Horn,Whitney E. Hornsby,Jouke-Jan Hottenga,Hongyan Huang,Jie Huang,Alicia Huerta-Chagoya,Jennifer E. Huffman,Yi Jen Hung,Shaofeng Huo,Mi Yeong Hwang,H. Iha,Daisuke Ikeda,Masato Isono,Anne U. Jackson,Susanne Jäger,Iris E. Jansen,Ingegerd Johansson,Jost B. Jonas,Anna Jonsson,Torben Jørgensen,Ioanna P. Kalafati,Masahiro Kanai,Stavroula Kanoni,Line Lund Kårhus,Anuradhani Kasturiratne,Tomohiro Katsuya,Takahisa Kawaguchi,Rachel L. Kember,Katherine A. Kentistou,Han Na Kim,Young-Jin Kim,Marcus E. Kleber,Maria J. Knol,Azra Kurbasic,Marie Lauzon,Phuong Le,Rod A. Lea,Jong-Young Lee,Hampton L. Leonard,Shengchao A. Li,Xiaohui Li,Xiaoyin Li,Jin Liang,Honghuang Lin,Shih-Yi Lin,Jun Liu,Xueping Liu,Ken Sin Lo,Jirong Long,Laura Lorés-Motta,Jian'an Luan,Valeriya Lyssenko,Leo-Pekka Lyytikäinen,Anubha Mahajan,Vasiliki Mamakou,Massimo Mangino,Ani Manichaikul,Jonathan Marten,Manuel Mattheisen,L. Mavarani,Aaron McDaid,Karina Meidtner,Tori L. Melendez,Josep M. Mercader,Yuri Milaneschi,Jason E. Miller,Iona Y. Millwood,Pashupati P. Mishra,Ruth Mitchell,Line Tang Møllehave,Anna Morgan,Soeren Mucha,Matthias Munz,Masahiro Nakatochi,Christopher P. Nelson,Maria Nethander,Chu Won Nho,Aneta Aleksandra Nielsen,Ilja M. Nolte,Suraj S. Nongmaithem,Raymond Noordam,Ioanna Ntalla,Teresa Nutile,Anita Pandit,Paraskevi Christofidou,Katri Pärna,Marc Pauper,Eva R. B. Petersen,Liselotte Petersen,Niina Pitkänen,Ozren Polasek,Alaitz Poveda,Michael Preuss,Saiju Pyarajan,Laura M. Raffield,Hiromi Rakugi,Julia Ramirez,Asif Rasheed,Dennis Raven,Nigel W. Rayner,Carlos Riveros,Rebecca Rohde,Daniela Ruggiero,Sanni Ruotsalainen,Kathleen A. Ryan,Maria Sabater-Lleal,Richa Saxena,Markus Scholz,Anoop K. Sendamarai,Botong Shen,Jingchunzi Shi,Jae Hun Shin,Carlo Sidore,Xueling Sim,Colleen M. Sitlani,Roderick C. Slieker,Roelof A.J. Smit,Jennifer A. Smith,Laura Smyth,Lorraine Southam,Valgerdur Steinthorsdottir,Liangdan Sun,Fumihiko Takeuchi,Divya Sri Priyanka Tallapragada,Kent D. Taylor,Bamidele O. Tayo,Catherine Tcheandjieu,Natalie Terzikhan,Paola Tesolin,Alexander Teumer,Elizabeth Theusch,Deborah J. Thompson,Gudmar Thorleifsson,Paul R. H. J. Timmers,Stella Trompet,Constance Turman,Simona Vaccargiu,Sander W. van der Laan,Peter J. van der Most,Jan B. van Klinken,Jessica van Setten,Shefali S. Verma,Niek Verweij,Yogasudha Veturi,Carol A. Wang,Chaolong Wang,Lihua Wang,Zhe Wang,Helen R. Warren,Wenjie Wei,Ananda R. Wickremasinghe,Matthias Wielscher,Kerri L. Wiggins,Bendik S. Winsvold,Andrew Wong,Yang Wu,Matthias Wuttke,Rong Xi,Tian Xie,Ken Yamamoto,Jingyun Yang,Jie Yao,Hannah Young,Noha A. Yousri,Lingyao Zeng,Weihua Zhang,Xinyuan Zhang,Jing Hua Zhao,Wei Zhao,Wei Zhou,Martina E. Zimmermann,Magdalena Zoledziewska,Linda S. Adair,Hieab H.H. Adams,Carlos A. Aguilar-Salinas,Fahd Al-Mulla,Donna K. Arnett,Folkert W. Asselbergs,Bjørn Olav Åsvold,John Attia,Bernhard Banas,Stefania Bandinelli,David A. Bennett,Tobias Bergler,Dwaipayan Bharadwaj,Ginevra Biino,Hans Bisgaard,Eric Boerwinkle,Carsten A. Böger,Klaus Bønnelykke,Dorret I. Boomsma,Anders D. Børglum,Judith B. Borja,Claude Bouchard,Donald W. Bowden,Ivan Brandslund,Ben Michael Brumpton,Julie E. Buring,Mark J. Caulfield,John C. Chambers,Giriraj R. Chandak,Stephen J. Chanock,Nish Chaturvedi,Yii-Der Ida Chen,Zhengming Chen,Ching-Yu Cheng,Ingrid E. Christophersen,Marina Ciullo,John W. Cole,Francis S. Collins,Richard S. Cooper,Miguel Cruz,Francesco Cucca,L. Adrienne Cupples,Michael J. Cutler,Scott M. Damrauer,Thomas Meinertz Dantoft,Gert J. de Borst,Lisette C. P. G. M. de Groot,Philip L. De Jager,Dominique P.V. de Kleijn,H. Janaka de Silva,George Dedoussis,Anneke I. den Hollander,Shufa Du,Douglas F. Easton,Petra J. M. Elders,A. Heather Eliassen,Patrick T. Ellinor,Sölve Elmståhl,Jeanette Erdmann,Michele K. Evans,Diane Fatkin,Bjarke Feenstra,Mary F. Feitosa,Luigi Ferrucci,Ian Ford,Myriam Fornage,Andre Franke,Paul W. Franks,Barry I. Freedman,Paolo Gasparini,Christian Gieger,Giorgia Girotto,Michael E. Goddard,Yvonne M. Golightly,Clicerio González-Villalpando,Penny Gordon-Larsen,Harald Grallert,Struan F.A. Grant,Niels Grarup,Lyn R. Griffiths,Leif Groop,Vilmundur Gudnason,Christopher A. Haiman,Hakon Hakonarson,Torben Hansen,Catharina A. Hartman,Andrew T. Hattersley,Caroline Hayward,Susan R. Heckbert,Chew-Kiat Heng,Christian Hengstenberg,Alex W. Hewitt,Haretsugu Hishigaki,Carel B. Hoyng,Paul L. Huang,Wei Huang,Steven C. Hunt,Kristian Hveem,Elina Hyppönen,William G. Iacono,Sahoko Ichihara,M. Arfan Ikram,Carmen R. Isasi,Rebecca D. Jackson,Marjo-Ritta Jarvelin,Zidan Jin,Karl-Heinz Jöckel,Peter K. Joshi,Pekka Jousilahti,J. Wouter Jukema,Mika Kähönen,Yoichiro Kamatani,Kui Dong Kang,Jaakko Kaprio,Sharon L.R. Kardia,Fredrik Karpe,Norihiro Kato,Frank Kee,Thorsten Kessler,Amit Khera,Chiea Chuen Khor,Lambertus A. Kiemeney,Bong-Jo Kim,EunGyul Kim,Hyung Lae Kim,Paulus Kirchhof,M Kivimaki,Woon-Puay Koh,Heikki A. Koistinen,Genovefa Kolovou,Jaspal S. Kooner,Charles Kooperberg,Anna Köttgen,Peter Kovacs,Adriaan O. Kraaijeveld,Peter Kraft,R. Krauß,Meena Kumari,Zoltán Kutalik,Markku Laakso,Leslie A. Lange,Claudia Langenberg,Lenore J. Launer,Loic Le Marchand,Hye Jin Lee,Nanette R. Lee,Terho Lehtimäki,Huaixing Li,Liming Li,Wolfgang Liebig,Xu（林旭） Lin,Lars Lind,Allan Linneberg,Ching-Ti Liu,Jianjun Liu,Markus Loeffler,Barry London,Steven A. Lubitz,Stephen J. Lye,David A. Mackey,Reedik Mägi,Patrik K. E. Magnusson,Gregory M. Marcus,Pedro Marques Vidal,Nicholas G. Martin,Winfried März,Fumihiko Matsuda,Robert W. McGarrah,Matt McGue,Amy Jayne McKnight,Sarah E. Medland,Dan Mellström,Andres Metspalu,Braxton D. Mitchell,Paul Mitchell,Dennis O. Mook-Kanamori,Andrew D. Morris,Lorelei A. Mucci,Patricia B. Munroe,Mike A. Nalls,Saman Nazarian,Amanda E. Nelson,Matt Neville,Christopher Newton-Cheh,Christopher Sivert Nielsen,Markus M. Nöthen,Claes Ohlsson,Albertine J. Oldehinkel,Lorena Orozco,Katja Pahkala,Päivi Pajukanta,Colin N. A. Palmer,Esteban J. Parra,Cristian Pattaro,Oluf Pedersen,Craig E. Pennell,Brenda W.J.H. Penninx,Louis Pérusse,Annette Peters,Patricia A. Peyser,David J. Porteous,Danielle Posthuma,Chris Power,Peter P. Pramstaller,Michael A. Province,Qibin Qi,Jia Qu,Daniel J. Rader,Olli T. Raitakari,Sarju Ralhan,Loukianos S. Rallidis,Dabeeru C. Rao,Susan Redline,Dermot F. Reilly,Alexander P. Reiner,Sang Youl Rhee,Paul M. Ridker,Michiel Rienstra,Samuli Ripatti,Marylyn D. Ritchie,Dan M. Roden,Frits R. Rosendaal,Jerome I. Rotter,Igor Rudan,Femke Rutters,Charumathi Sabanayagam,Danish Saleheen,Veikko Salomaa,Nilesh J. Samani,Dharambir K. Sanghera,Naveed Sattar,Börge Schmidt,E. E. Schmidt,Reinhold Schmidt,Matthias B. Schulze,Heribert Schunkert,Laura J. Scott,Rodney J. Scott,Peter S. Sever,Eric J. Shiroma,M. Benjamin Shoemaker,Xiao-Ou Shu,Eleanor M. Simonsick,Mario Sims,Jai Rup Singh,Andrew B. Singleton,Moritz F. Sinner,J. Gustav Smith,Harold Snieder,Tim D. Spector,Meir J. Stampfer,Klaus Stark,David P. Strachan,Leen M 't Hart,Yasuharu Tabara,Hua Tang,Jean-Claude Tardif,Thangavel Alphonse Thanaraj,Nicholas J. Timpson,Anke Tönjes,Angelo Tremblay,Tiinamaija Tuomi,Jaakko Tuomilehto,María Teresa Tusié-Luna,André G. Uitterlinden,Rob M. van Dam,P. Van der Harst,Nathalie van der Velde,Cornelia M. van Duijn,Natasja M. van Schoor,Veronique Vitart,Uwe Völker,Peter Vollenweider,Henry Völzke,Scott I. Vrieze,Niels Wacher-Rodarte,Mark Walker,Ya Xing Wang,Nicholas J. Wareham,Richard M. Watanabe,Hugh Watkins,David R. Weir,Thomas Werge,Elisabeth Widen,Lynne R. Wilkens,Gonneke Willemsen,Walter C. Willett,James F. Wilson,Tien Yin Wong,Jeong Taek Woo,Alan F. Wright,Jer-Yuarn Wu,Huichun Xu,Chittaranjan S. Yajnik,Mitsuhiro Yokota,Jian-Min Yuan,Eleftheria Zeggini,Babette S. Zemel,Wei Zheng,Xiaofeng Zhu,Joseph M. Zmuda,Alan B. Zonderman,John-Anker Zwart,Daniel I. Chasman,Yoon Shin Cho,Iris M. Heid,Mark I. McCarthy,Maggie C.Y. Ng,Christopher J. O'Donnell,Fernando Rivadeneira,Unnur Thorsteinsdottir,Yan V. Sun,E. Shyong Tai,Michael Boehnke,Panos Deloukas,Anne E. Justice,Cecilia M. Lindgren,Ruth J. F. Loos,Karen L. Mohlke,Kari E. North,Kari Stefansson,Robin G. Walters,Thomas W. Winkler,Kristin L. Young,Po-ru Loh,Tõnu Esko,Themistocles L. Assimes,Adam Auton,Gonçalo R. Abecasis,Cristen J. Willer,Adam E. Locke,Sonja I. Berndt,Guillaume Lettre,Timothy M. Frayling,Yukinori Okada,Andrew R. Wood,Peter M. Visscher,Joel N. Hirschhorn +617 more
TL;DR: In this article , the authors show that common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes.