Jiayan Lian
Sun Yat-sen University
6 Papers
36 Citations
Jiayan Lian is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Carcinogenesis & Downregulation and upregulation. The author has an hindex of 4, co-authored 4 publications.
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Papers
The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α.
Ying Wang,Wanyuan Chen,Jiayan Lian,Haibo Zhang,Bo Yu,Minjun Zhang,Fangqiang Wei,Jianhui Wu,Jiaxiang Jiang,Yongshi Jia,Fan Mo,Shirong zhang,Xiaodong Liang,Mou Xiaozhou,Jianming Tang +14 more
TL;DR: The results demonstrate that PVT1 serves an oncogenic role and plays an important role in radiosensitivity in malignant NPC via activating the KAT2A acetyltransferase and stabilizing HIF-1α.
Long non-coding RNA DANCR promotes colorectal tumor growth by binding to lysine acetyltransferase 6A.
Jiayan Lian,Haibo Zhang,Fangqiang Wei,Qiang Li,Yanwei Lu,Bo Yu,Lili Yu,Xiaodong Liang,Yang Wen,Ketao Jin,Jianming Tang,Wenlin Xie +11 more
TL;DR: The data indicated that DANCR functions as an oncogenic lncRNA that promotes tumor development and progression and may be a target molecule for colorectal cancer treatment.
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Positive feedback loop of hepatoma-derived growth factor and β-catenin promotes carcinogenesis of colorectal cancer.
Jiayan Lian,Jianming Tang,Huijuan Shi,Hui Li,Tiantian Zhen,Wenlin Xie,Fenfen Zhang,Yang Yang,Anjia Han +8 more
TL;DR: The results suggest that HDGF and β-catenin interacts as a positive feedback loop, which plays an important role in carcinogenesis and progression of CRC.
CDK2-activated TRIM32 phosphorylation and nuclear translocation promotes radioresistance in triple-negative breast cancer.
Jianming Tang,Jiayan Lian,Yumei Huang,Yaqing Zhang,Yanwei Lu,Guansheng Zhong,Yaqi Wang,Zhitao Zhang,Xin Bai,Min Fang,Luming Wu,Haofei Shen,Jingyuan Wu,Yiqing Wang,Haibo Zhang +14 more
TL;DR: It is demonstrated that regulating the CDK2/TRIM32/STAT3 pathway is a promising strategy for reducing radioresistance in TNBC.
11
MicroRNA-325-3p Targets Human Epididymis Protein 4 to Relieve Right Ventricular Fibrosis in Rats with Pulmonary Arterial Hypertension
TL;DR: Overexpression of miR-325-3p could target HE4 to relieve right ventricular fibrosis in rats with PAH and could provide new targets and strategies forright ventricular Fibrosis in PAH.