Jiaqi Li
6 Papers
Jiaqi Li is an academic researcher. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 2, co-authored 5 publications.
Chat about Author
Papers
Microneedle-based interstitial fluid extraction for drug analysis: Advances, challenges, and prospects
TL;DR: In this article , the authors review the progress in drug analysis based on microneedle-assisted interstitial fluid extraction and discuss the related future opportunities and challenges, as well as the integration of wearable devices for real-time dose modification.
35
Celastrol inhibits lung cancer growth by triggering histone acetylation and acting synergically with HDAC inhibitors.
Geer Chen,Xiao-song Zhu,Jiaqi Li,Yao Qian Zhang,Xiaoxuan Wang,Ren Zhang,Xinchen Qin,Xi Chen,Junyi Wang,Wei Ling Liao,Zongjin Wu,Lu Lu,Weiyu Wu,Haijie Yu,Lijuan Ma +14 more
TL;DR: In this article , a barcode sequencing of a eukaryotic genome-wide deletion library revealed that histone modifications, especially histone acetylation associated with the NuA4 histoneacetyltransferase complex, were involved in the anti-proliferation actions of celastrol.
17
Suppression of PD‐L1 release from small extracellular vesicles promotes systemic anti‐tumor immunity by targeting ORAI1 calcium channels
Xi Chen,Jiaqi Li,Ren Zhang,Yao Qian Zhang,Xiaoxuan Wang,Elaine Lai-Han Leung,Lijuan Ma,Vincent Wai-Sun Wong,Liang Liu,Erwin Neher,Haijie Yu +10 more
TL;DR: In this paper , the role of three Ca2+dependent proteins in regulating release of PD-L1-containing sEVs, as well as on the growth of tumors in mouse models, is investigated.
16
Formosanin C inhibits non-small-cell lung cancer progression by blocking MCT4/CD147-mediated lactate export.
Jiaqi Li,Zongjin Wu,Geer Chen,Xiaoxuan Wang,Xiao-Yu Zhu,Yao Qian Zhang,Ren Zhang,Weiyu Wu,Yi-Zhun Zhu,Lijuan Ma,Haijie Yu +10 more
TL;DR: In this paper , the effect of Formosanin C (FC) on lung cancer metabolism was investigated using 1H NMR metabolomics approach to screen the differential metabolites in H1299 cells and the culture medium, and an allograft tumor model was employed to investigate the anti-tumor effects of FC.
8
Chinese dragon's blood ethyl acetate extract suppresses gastric cancer progression through induction of apoptosis and autophagy mediated by activation of MAPK and downregulation of the mTOR‐Beclin1 signalling cascade
Lishan Ouyang,Jiaqi Li,Xiao-Nan Chen,Hui-Ming Huang,Ying-Ying Tian,Xingxing Li,Daoran Pang,Xue-Jiao Wei,Jin-Xin Xie,Longyan Wang,Dongxia Liu,Peng-Fei Tu,Jun Li,Zhongdong Hu +13 more
TL;DR: It is demonstrated that Chinese dragon's blood ethyl acetate extract (CDBEE) suppressed the proliferative and metastatic potential of human gastric cancer MGC-803 and HGC-27 cells and exhibited potent anti-GC efficacy in vivo without obvious toxicity or side effects.
6