Jianmin Wang
Peking Union Medical College
18 Papers
87 Citations
Jianmin Wang is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Antibody & Viral replication. The author has an hindex of 12, co-authored 18 publications.
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Papers
Virome Analysis for Identification of Novel Mammalian Viruses in Bat Species from Chinese Provinces
Zhiqiang Wu,Xianwen Ren,Li Yang,Yongfeng Hu,Jian Yang,Guimei He,Junpeng Zhang,Jie Dong,Lilian Sun,Jiang Du,Liguo Liu,Ying Xue,Jianmin Wang,Fan Yang,Shuyi Zhang,Qi Jin +15 more
TL;DR: The range of bat viromes, including viruses from mammals, insects, fungi, plants, and phages, in 11 insectivorous bat species common in six provinces of China are described and the complete or partial genome sequences of 13 novel mammalian viruses are identified.
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Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset
Zhe Chen,Linlin Bao,Cong Chen,Tingting Zou,Ying Xue,Fengdi Li,Qi Lv,Songzhi Gu,Xiaopan Gao,Sheng Cui,Jianmin Wang,Chuan Qin,Qi Jin +12 more
TL;DR: A human monoclonal antibody, MCA1, directly targeting the receptor-binding domain of Middle East respiratory syndrome coronavirus (MERS-CoV) S glycoprotein, was isolated from a human survivor and completely inhibited viral replication in common marmosets.
Anti-Enterovirus 71 Effects of Chrysin and Its Phosphate Ester
TL;DR: Chrysin could suppress viral 3Cpro activity in vitro by using the predicting program Autodock 4.0 and an in vitro protease inhibition assay, and demonstrated more potent antiviral activity against EV71.
Human monoclonal antibodies targeting the haemagglutinin glycoprotein can neutralize H7N9 influenza virus
Zhe Chen,Jianmin Wang,Linlin Bao,Li Guo,Wei-Jia Zhang,Ying Xue,Hongli Zhou,Yan Xiao,Jianwei Wang,Fan Wu,Ying Deng,Chuan Qin,Qi Jin +12 more
TL;DR: Two human monoclonal antibodies, HNIgGA6 and HNIGGB5, are characterized by screening a Fab antibody phage library derived from patients who recovered from H7N9 infection and exhibit high neutralizing activity against H7n9 virus in cells.
COPI is required for enterovirus 71 replication.
Jianmin Wang,Zhiqiang Wu,Qi Jin +2 more
TL;DR: It is reported that COPi, but not COPII, is required for EV71 replication, and EV71 2C protein interacted with COPI subunits by co-immunoprecipitation and GST pull-down assay, indicating that COPI coatomer might be directed to the viral replication complex through viral 2Cprotein.