Jianjiong Li
Chinese Academy of Sciences
30 Papers
54 Citations
Jianjiong Li is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Chemistry & Nitrilase. The author has an hindex of 4, co-authored 19 publications.
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Papers
Biocatalytic Access to 1,4-Diazepanes via Imine Reductase-Catalyzed Intramolecular Asymmetric Reductive Amination
Zefei Xu,Peiyuan Yao,Xiang Sheng,Jinlong Li,Jianjiong Li,Shanshan Yu,Jinhui Feng,Qiaqing Wu,Dunming Zhu +8 more
TL;DR: An enzymatic intramolecular asymmetric reductive amination has been developed for the synthesis of chiral 1,4-diazepanes and several enantiocomplementary IREDs were identified.
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Inverting the Enantiopreference of Nitrilase-Catalyzed Desymmetric Hydrolysis of Prochiral Dinitriles by Reshaping the Binding Pocket with a Mirror-Image Strategy
Shanshan Yu,Jinlong Li,Peiyuan Yao,Jinhui Feng,Yunfeng Cui,Jianjiong Li,Liu Xiangtao,Qiaqing Wu,Jianping Lin,Dunming Zhu +9 more
TL;DR: This study may offer a general strategy to switch the stereopreference of other nitrilases and other classes of enzymes toward the desymmetric reactions of prochiral substrates with two identical reactive functional groups, that are often desirable in asymmetric synthesis.
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Microbial stereospecific reduction of 3-quinuclidinone with newly isolated Nocardia sp. and Rhodococcus erythropolis
TL;DR: Two bacterium strains, Nocardia sp.
19
Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2-Arylethylamines via a Chemoenzymatic Approach.
TL;DR: A group of active imine reductases were identified to convert the imine precursors into the corresponding enantiocomplementary fused- ring THIQs and THβCs with high enantioselectivity and conversion, establishing an efficient and green chemoenzymatic approach to fused-ring alkaloids from 2-arylethylamines.
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Enzymatic synthesis of 3-hydroxypropionic acid at high productivity by using free or immobilized cells of recombinant Escherichia coli
Shanshan Yu,Shanshan Yu,Peiyuan Yao,Jianjiong Li,Jie Ren,Jing Yuan,Jinhui Feng,Min Wang,Qiaqing Wu,Dunming Zhu +9 more
TL;DR: It is demonstrated that the immobilized cells have potential industrial application for the synthesis of 3-HP using free or immobilized recombinant Escherichia coli BL21(DE3) cells harboring a nitrilase gene from environmental sample (NIT190).
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