Jiani Li
Baylor College of Medicine
8 Papers
33 Citations
Jiani Li is an academic researcher from Baylor College of Medicine. The author has contributed to research in topics: Population & Ribonucleotide reductase. The author has an hindex of 7, co-authored 8 publications. Previous affiliations of Jiani Li include University of Minnesota.
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Papers
The GenomeAsia 100K Project enables genetic discoveries across Asia
Jeffrey D. Wall,Eric Stawiski,Aakrosh Ratan,Hie Lim Kim,Changhoon Kim,Ravi Gupta,Kushal Suryamohan,Elena S. Gusareva,Rikky W. Purbojati,Tushar Bhangale,Vadim Stepanov,Vladimir Kharkov,Markus S. Schröder,Vedam L. Ramprasad,Jennifer Tom,Steffen Durinck,Qixin Bei,Jiani Li,Joseph Guillory,Phalkek Sameer,Analabha Basu,Jeremy Stinson,Sandhya Nair,Sivasankar Malaichamy,Nidhan K. Biswas,John C. Chambers,Keith C. Cheng,Joyner T. George,Seik-Soon Khor,Jong Il Kim,Belong Cho,Ramesh Menon,Thiramsett Sattibabu,Akshi Bassi,Manjari Deshmukh,Anjali Verma,Vivek Gopalan,Jong-Yeon Shin,Mahesh Pratapneni,Sam Santhosh,Katsushi Tokunaga,Badrul Munir Md-Zain,Kok-Gan Chan,Madasamy Parani,Purushothaman Natarajan,Michael A. Hauser,R. Rand Allingham,Santiago-Turla,Arkasubhra Ghosh,Santosh Gopi Krishna Gadde,Christian Fuchsberger,Lukas Forer,Sebastian Schoenherr,Herawati Sudoyo,J. Stephen Lansing,Jonathan S. Friedlaender,George Koki,Murray P. Cox,Michael F. Hammer,Tatiana M. Karafet,Khai C. Ang,Syed Qasim Mehdi,Venkatesan Radha,Viswanathan Mohan,Partha P. Majumder,Somasekar Seshagiri,Jeong-Sun Seo,Stephan C. Schuster,Andrew S. Peterson +68 more
TL;DR: The pilot phase of the GenomeAsia 100K Project catalogues genetic variation, population structure and disease associations to facilitate genetic studies in Asian populations and increase representation in genetics studies worldwide.
A Prototypic Lysine Methyltransferase 4 from Archaea with Degenerate Sequence Specificity Methylates Chromatin Proteins Sul7d and Cren7 in Different Patterns
Yanling Niu,Yisui Xia,Sishuo Wang,Jiani Li,Caoyuan Niu,Xiao Li,Yuehui Zhao,Huiyang Xiong,Zhen Li,Huiqiang Lou,Qinhong Cao +10 more
TL;DR: It is shown that a widespread lysine methyltransferase from Archaea (aKMT4), bears striking structural and functional resemblance to the core of distantly related eukaryotic KMT4/Dot1, and may be regulated by the local chromatin environment, albeit as a promiscuous enzyme required for extensive and variegated lysines methylation in Sulfolobus.
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Rho Guanine Nucleotide Exchange Factor ARHGEF17 Is a Risk Gene for Intracranial Aneurysms.
Xinyu Yang,Jiani Li,Yabo Fang,Zhen Zhang,Daqing Jin,Daqing Jin,Xingdong Chen,Yan Zhao,Mengqi Li,Linchun Huan,Thomas A. Kent,Jing Fei Dong,Rongcai Jiang,Shuyuan Yang,Li Jin,Jianning Zhang,Tao P. Zhong,Tao P. Zhong,Fuli Yu,Fuli Yu +19 more
- 01 Jul 2018
TL;DR: The results provide compelling evidence that ARHGEF17 is a risk gene for IA, and endothelial lesions were identified exclusively on cerebral blood vessels in the arhgef17-deficient zebrafish.
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Identification of African-Specific Admixture between Modern and Archaic Humans
Jeffrey D. Wall,Aakrosh Ratan,Eric Stawiski,Hie Lim Kim,Changhoon Kim,Ravi Gupta,Kushal Suryamohan,Elena S. Gusareva,Rikky W. Purbojati,Tushar Bhangale,Vadim Stepanov,Vladimir Kharkov,Markus S. Schrӧder,Vedam L. Ramprasad,Jennifer Tom,Steffen Durinck,Qixin Bei,Jiani Li,Joseph Guillory,Samir Phalke,Analabha Basu,Jeremy Stinson,Sandhya Nair,Sivasankar Malaichamy,Nidhan K. Biswas,John C. Chambers,Keith C. Cheng,Joyner T. George,Seik-Soon Khor,Jong Il Kim,Belong Cho,Ramesh Menon,Thiramsetti Sattibabu,Akshi Bassi,Manjari Deshmukh,Anjali Verma,Vivek Gopalan,Jong-Yeon Shin,Mahesh Pratapneni,Sam Santhosh,Katsushi Tokunaga,Badrul Munir Md-Zain,Kok-Gan Chan,Madasamy Parani,Purushothaman Natarajan,Michael A. Hauser,R. Rand Allingham,Cecilia Santiago-Turla,Arkasubhra Ghosh,Santosh Gopi Krishna Gadde,Christian Fuchsberger,Lukas Forer,Sebastian Shoenherr,Herawati Sudoyo,J. Stephen Lansing,Jonathan S. Friedlaender,George Koki,Murray P. Cox,Michael F. Hammer,Tatiana M. Karafet,Khai C. Ang,Syed Qasim Mehdi,Venkatesan Radha,Viswanathan Mohan,Partha P. Majumder,Sekar Seshagiri,Jeong-Sun Seo,Stephan C. Schuster,Andrew S. Peterson +68 more
TL;DR: This work searches for evidence of archaic admixture from a worldwide panel of 1,667 individuals using an approach that does not require the presence of an archaic human reference genome and finds evidence for at least one archaic admixtures event in sub-Saharan Africa.
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Complexity and diversity of F8 genetic variations in the 1000 genomes.
TL;DR: Hemophilia A is an X‐linked bleeding disorder caused by deleterious mutations in the coagulation factor VIII gene (F8), and information on F8 variants in individuals of more diverse ethnic backgrounds is limited.
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