Jianguo Gu
Tohoku Pharmaceutical University
162 Papers
707 Citations
Jianguo Gu is an academic researcher from Tohoku Pharmaceutical University. The author has contributed to research in topics: Integrin & Cell adhesion. The author has an hindex of 54, co-authored 151 publications. Previous affiliations of Jianguo Gu include Osaka University & Columbia University.
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Papers
Integrin β1 in Pancreatic Cancer: Expressions, Functions, and Clinical Implications
Jiajia Li,Li-Yao Peng,Qun Chen,Zi-ming Ye,Tiantian Zhao,Sicong Hou,Jianguo Gu,Qing-shan Hang +7 more
TL;DR: The various signaling pathways that are mediated by integrins in PC are presented and the multiple functions of integrin β1 in malignant behaviors of PC are emphasized, focusing on the roles ofIntegrinβ1 in the malignant behavior of PC.
α1,6-Fucosyltransferase contributes to cell migration and proliferation as well as to cancer stemness features in pancreatic carcinoma
TL;DR: In this paper, the expression levels of cancer stemness markers such as EpCAM, CXCR4, c-Met, and CD133 were decreased in the FUT8-KO cells compared with wild-type cells.
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Effect of exogenous decorin on cell morphology and attachment of decorin-deficient fibroblasts.
Jianguo Gu,Yoshinao Wada +1 more
TL;DR: It is suggested that decorin exhibits an anti-adhesion property in a fibroblast culture system and that the deficiency is responsible for the morphological change observed in this patient's fibroblasts.
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Aberrant Expressions of Decorin and Biglycan Genes in the Carbohydrate-Deficient Glycoprotein Syndrome
Jianguo Gu,Yoshinao Wada +1 more
TL;DR: Examination of the expressions of the small proteoglycans decorin and biglycan in cultured skin fibroblasts from a patient with CDGS Type-I found responses to interleukin-1 beta and transforming growth factor-beta 1 were apparently abnormal.
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Recombinant Expression and Characterization of a Novel Fibronectin Isoform Expressed in Cartilaginous Tissues
Tomohiro Kozaki,Yoshito Matsui,Jianguo Gu,Ryoko Nishiuchi,Nobuo Sugiura,Koji Kimata,Keiichi Ozono,Hideki Yoshikawa,Kiyotoshi Sekiguchi +8 more
TL;DR: It is likely that cartilage-type FN has evolved to adapt itself to the non-fibrillar structure of the cartilage matrix through acquisition of a novel mechanism of alternative pre-mRNA splicing.
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