10 Papers
12 Citations
Jian Yu is an academic researcher from Second Military Medical University. The author has contributed to research in topics: Medicine & Hepatocellular carcinoma. The author has an hindex of 5, co-authored 5 publications.
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Papers
Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma.
Jian Yu,Qing-guo Xu,Zhen-guang Wang,Yuan Yang,Ling Zhang,Jin-zhao Ma,Shuhan Sun,Fu Yang,Weiping Zhou +8 more
TL;DR: In vitro and in vivo data showed that cSMARCA5 inhibits the growth and migration of hepatocellular carcinoma cells, making it a potential therapeutic target.
773
Long noncoding RNA FTX inhibits hepatocellular carcinoma proliferation and metastasis by binding MCM2 and miR-374a.
Feng Liu,Ji-hang Yuan,Jinfeng Huang,Fu Yang,Tian-tian Wang,Jin-zhao Ma,Ling Zhang,Chuan-chuan Zhou,Fudi Wang,Jian Yu,Weiping Zhou,Shu-han Sun +11 more
TL;DR: Results suggest that lnc-FTX may act as a tumor suppressor in HCC through physically binding miR-374a and MCM2 and may potentially contribute to HCC treatment.
181
Circular RNA cFAM210A, degradable by HBx, inhibits HCC tumorigenesis by suppressing YBX1 transactivation
Jian Yu,Wen Li,Guo-Jun Hou,Da-peng Sun,Yuan Yang,Sheng-Xian Yuan,Zhi-hui Dai,Hao Yin,Shu-han Sun,Gang Huang,Weiping Zhou,Fu Yang +11 more
TL;DR: It is found that cFAM210A (a circular RNA derived from the third exon of transcript NM_001098801 of the FAM210A gene; CircBase ID: hsa_circ_0003979) can be silenced by HBx and is identified as a potential target in the prevention and treatment of HBV-related HCC.
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NSUN5 promotes progression and predicts poor prognosis in hepatocellular carcinoma
Xiao-wen Zhang,Luyi Wu,Huirong Liu,Yan Huang,Qin Qi,Rui Zhong,Lu Zhu,Chunfang Gao,Lin Zhou,Jian Yu,Huan-gan Wu +10 more
TL;DR: NSUN5 may promote the progression of HCC by enhancing translation, thus making it a potential target for HCC treatment, according to data from both TCGA database and present study cohorts.
Paraoxonase 3 inhibits cell proliferation and serves as a prognostic predictor in hepatocellular carcinoma.
Jie Cai,Sheng-xian Yuan,Fu Yang,Qi-fei Tao,Yuan Yang,Qing-guo Xu,Zhen-guang Wang,Jian Yu,Kong-ying Lin,Zongyan Wang,Jin-zhao Ma,Chuan-chuan Zhou,Fang Wang,Shuhan Sun,Weiping Zhou +14 more
TL;DR: The studies reveal the cell proliferation inhibitory function of PON3 and offer a potential prognostic predictor and therapeutic target for HCC.