Jian Ma
University of Helsinki
15 Papers
233 Citations
Jian Ma is an academic researcher from University of Helsinki. The author has contributed to research in topics: Synovial membrane & Matrix metalloproteinase. The author has an hindex of 11, co-authored 15 publications. Previous affiliations of Jian Ma include Helsinki University Central Hospital.
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Papers
New collagenolytic enzymes/cascade identified at the pannus-hard tissue junction in rheumatoid arthritis : destruction from above
Yrjö T. Konttinen,A Ceponis,Michiaki Takagi,Mari Ainola,Timo Sorsa,Meeri Sutinen,Tuula Salo,Jian Ma,Seppo Santavirta,Motoharu Seiki +9 more
TL;DR: Results indicate that components of the ternary MT1-MMP/TIMP-2/MMP-2 complex are coexpressed in the normal synovial lining and in its pathological extension on the hyaline articular cartilage.
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Collagenases in Different Categories of Peri-implant Vertical Bone Loss
Jian Ma,Uula Kitti,Olli Teronen,Timo Sorsa,Ville Husa,P. Laine,Hanne Rönkä,Tuula Salo,Christian Lindqvist,Yrjö T. Konttinen +9 more
TL;DR: Collagenase-2 and collagenase-3 were higher in the group which had lost > 3 mm of bone than in the two other groups, and they might participate in peri-implant osteolysis.
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Fibroblast biology: Signals targeting the synovial fibroblast in arthritis
TL;DR: Aggressive, transformed or transfected mesenchymal cells containing proto-oncogenes can act in the absence of lymphocytes, but whether these cells represent regressed fibroblasts, chondrocytes or bone marrow stem cells is unclear.
Gelatinase B is associated with peri‐implant bone loss
Jian Ma,Uula Kitti,Roeland Hanemaaijer,Olli Teronen,Timo Sorsa,Sirajedin S. Natah,Tensing Ek,Yrjö T. Konttinen,Yrjö T. Konttinen +8 more
TL;DR: Activation of gelatinase B together with elevated mGI eventually reflect active phases of peri-implantitis and may prove to be diagnostically useful.
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•Journal Article
Chondrocyte-mediated collagenolysis correlates with cartilage destruction grades in osteoarthritis
TL;DR: Collagenase-cleaved collagen--both native and denatured--increases as the severity of OA increases, assessed using a macroscopic clinical and microscopic histological grading system.
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