Jian Huang
Zhejiang University
1596 Papers
7.2K Citations
Jian Huang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 97, co-authored 1189 publications. Previous affiliations of Jian Huang include Wuhan University of Technology & Chinese National Human Genome Center.
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Papers
Activation of Src and transformation by an RPTPα splice mutant found in human tumours
Jian Huang,Ling Yao,Rongting Xu,Huacheng Wu,Min Wang,Brian S. White,David Shalloway,Xinmin Zheng,Xinmin Zheng +8 more
TL;DR: The transformed cells were tumourigenic in nude mice, suggesting that RPTPα245‐induced activation of Src in the human tumours may have contributed to carcinogenesis.
Investigation of O3–NOx–VOCs chemistry and pollutant dispersion in street canyons with various aspect ratios by CFD simulations
TL;DR: Based on the OpenFOAM environment, a new CFD code named as APFoam coupling turbulence with the complex photochemical mechanism of NO x -O 3 -VOCs reactions has been developed as discussed by the authors .
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Effect of IL-18 gene promoter polymorphisms on prostate cancer occurrence and prognosis in Han Chinese population.
TL;DR: There is evidence that the IL-18 gene promoter polymorphism -137G/ C influences the prognosis of prostate cancer patients in androgen deprivation therapy, although neither of the two SNPs contributes to prostate cancer development.
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Loosely-packed dynamical structures with partially-melted surface being the key for thermophilic argonaute proteins achieving high DNA-cleavage activity
Lirong Zheng,Huili Lu,Bing Zan,Song-bo Li,Hao Liu,Zhuo Liu,Jian Huang,Yongjia Liu,Fan Jiang,Qian Liu,Yan Feng,Liang Hong +11 more
TL;DR: It is suggested that the highly dynamical structure with a partially-melted surface, distinct from the low-temperature crystalline structure, could be a general strategy assumed by thermophilic pAgos to achieve the high DNA-cleavage activity.
Association of antidepressant and atypical antipsychotic use with cardiovascular events and mortality in a veteran population.
Tushar Acharya,Tushar Acharya,Sabeena Acharya,Steven Tringali,Steven Tringali,Jian Huang,Jian Huang +6 more
TL;DR: To determine the patterns of antidepressant and atypical antipsychotic use in a veteran population with depression, and to determine if an association exists between specific antidepressant classes and atopic antipsychotics and the occurrence of cardiovascular events and all‐cause mortality, a large number of veterans with depression are surveyed.
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