Jian-an Wang
Zhejiang University
383 Papers
995 Citations
Jian-an Wang is an academic researcher from Zhejiang University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 43, co-authored 306 publications. Previous affiliations of Jian-an Wang include Sir Run Run Shaw Hospital.
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Papers
Heat shock protein 90 protects rat mesenchymal stem cells against hypoxia and serum deprivation-induced apoptosis via the PI3K/Akt and ERK1/2 pathways.
Feng Gao,Xinyang Hu,Xiaojie Xie,Qiyuan Xu,Yaping Wang,Xianbao Liu,Meixiang Xiang,Yong Sun,Jian-an Wang +8 more
TL;DR: The cytoprotection of heat shock protein 90 improves MSC viability and protects MSCs against apoptosis induced by serum deprivation and hypoxia and demonstrated a novel and effective treatment strategy against MSC apoptosis in cell transplantation.
Human antigen R regulates autophagic flux by stabilizing autophagy-associated mRNA in calcific aortic valve disease.
Juan Fang,Yi Qian,Jinyong Chen,Dilin Xu,Naifang Cao,Gangjie Zhu,Wangxing Hu,Haochang Hu,Ningjing Qian,Shuangshuang Yang,Jian-an Wang,Xianbao Liu +11 more
TL;DR: In this article , the authors evaluated the role and underlying mechanisms of human antigen R (HuR)-mediated post-transcriptional regulation in CAVD and found that HuR was significantly upregulated in human calcified aortic valves and primary aortric valvular interstitial cells (VICs) following osteogenic stimulation.
Validation of a novel staging classification system based on the extent of cardiac damage among Chinese patients after transcatheter aortic valve replacement: A single‐center retrospective study
Qifeng Zhu,Zheng Yuan,Ye-Ming Xu,Jun Chen,Stella Ng,Abuduwufuer Yidilisi,Kaida Ren,Yuwen Chen,Wangxing Hu,Gangjie Zhu,Feng Liu,Mengqiu Dang,Yuxin He,Yuchao Guo,Jiaqi Fan,Xianbao Liu,Jian-an Wang +16 more
TL;DR: It is aimed to validate a novel staging system for aortic stenosis in a Chinese patient cohort undergoing transcatheter aortIC valve replacement (TAVR), and to compare this classification system to the traditional Society of Thoracic Surgeons (STS) score for TAVR risk stratification.
Emerging role of interleukin-13 in cardiovascular diseases: A ray of hope.
TL;DR: The role of IL-13 in the treatment of cardiovascular diseases is discussed in this article, where the authors summarize the advancement in the knowledge of the regulations and functions of interleukin (IL)-13 in CVDs.