Jiaming Chen
Shenyang Pharmaceutical University
13 Papers
Jiaming Chen is an academic researcher from Shenyang Pharmaceutical University. The author has contributed to research in topics: Medicine & Cancer. The author has an hindex of 3, co-authored 3 publications.
Chat about Author
Papers
Detection of cysteine- and lysine-based protein adductions by reactive metabolites of 2,5-dimethylfuran.
TL;DR: A novel and simple analytical platform to detect protein modification resulting from metabolic activation of model compound 2,5-dimethylfuran (DMF) and to define the structural identities of amino acid residues modified is developed.
22
Cytochrome P450 Mediated Bioactivation of Saracatinib
TL;DR: Inhibition and recombinant P450 enzyme incubation studies demonstrated that P450 3A4 was the primary enzyme responsible for the metabolic activation of saracatinib, and the metabolism study facilitates the understanding of correlation between sarcatinib-induced hepatotoxicity and bioactivation.
18
Tumor-Derived Exosome FGD5-AS1 Promotes Angiogenesis, Vascular Permeability, and Metastasis in Thyroid Cancer by Targeting the miR-6838-5p/VAV2 Axis
TL;DR: The results suggest that FGD5-AS1 in tumor-derived exoskeleton promotes angiogenesis, vascular permeability, and metastasis by regulating the endothelial miR-6838-5p/VAV2 axis and ultimately promotes the occurrence and development of TC.
Induction chemotherapy-based organ-preservation protocol improve the function preservation compared with immediate total laryngectomy for locally advanced hypopharyngeal cancer-Results of a matched-pair analysis.
Yifan Yang,Lifeng Feng,Qi Zhong,Yang Zhang,Zhigang Huang,Shurong Zhang,Shuling Li,Junmao Gao,Lizhen Hou,Hongzhi Ma,Shizhi He,Qian Shi,Meng Lian,Yanmin Shao,Xixi Shen,Jiaming Chen,Lingwa Wang,Haiyang Li,Shaoshi Chen,Jiaqi Xu,Ru Wang,Jugao Fang +21 more
TL;DR: In this paper , the authors performed a paired analysis to compare the therapeutic effect between the induction chemotherapy-based organ-preservation approach and immediate total laryngectomy in hypopharyngeal squamous cell carcinoma patients requiring total LCT.
3
A combined microinvasive trans-submandibular and nasendoscopy surgical approach to dissect recurrent or radiotherapy-insensitive nasopharyngeal carcinoma
Yanmin Shao,Jugao Fang,Qi Zhong,Lu Zhang,Chenglin Wang,Jiamin Zhang,Jiaming Chen,Lifeng Feng,Shizhi He,Hongzhi Ma,Lizhen Hou,Meng Lian,Qian Shi,Xixi Shen,Yifan Yang,Ru Wang +15 more
TL;DR: Patients with recurrent nasopharyngeal carcinoma after radiotherapy and radiotherapy-insensitive types of nasoph throat carcinoma, the combined microinvasive trans-submandibular and nasendoscopy surgical approach may be considered as an surgical options.
2