Jiamin Chen
Stanford University
29 Papers
36 Citations
Jiamin Chen is an academic researcher from Stanford University. The author has contributed to research in topics: Biology & microRNA. The author has an hindex of 12, co-authored 23 publications. Previous affiliations of Jiamin Chen include BC Cancer Agency & Kingston General Hospital.
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Papers
Single-Cell Genomic Characterization Reveals the Cellular Reprogramming of the Gastric Tumor Microenvironment.
Anuja Sathe,Susan M. Grimes,Billy T. Lau,Jiamin Chen,Carlos Suárez,Robert J. Huang,George A. Poultsides,Hanlee P. Ji +7 more
TL;DR: Single-cell gene expression studies revealed widespread reprogramming across multiple cellular elements in the gastric cancer TME, which facilitates understanding of tumor biology and enables identification of novel targets including for immunotherapy.
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MicroRNA-193b Represses Cell Proliferation and Regulates Cyclin D1 in Melanoma
Jiamin Chen,Harriet Feilotter,Geneviève C. Paré,Xiao Zhang,Joshua G. Pemberton,Cherif Garady,Dulcie Lai,Xiaolong Yang,Victor A. Tron +8 more
TL;DR: Functional studies indicate that miR-193b represses cell proliferation and regulates CCND1 expression and suggest that dysregulation of miR -193b may play an important role in melanoma development.
Single cell genomic characterization reveals the cellular reprogramming of the gastric tumor microenvironment
Anuja Sathe,Susan M. Grimes,Billy T. Lau,Jiamin Chen,Carlos Suárez,Robert J. Huang,George A. Poultsides,Hanlee P. Ji +7 more
TL;DR: The power of single-cell genomics is leveraged to characterize the heterogenous cell types and states in the tumor microenvironment (TME) and enables the identification of novel molecular targets including for cancer immunotherapy.
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An array-based analysis of microRNA expression comparing matched frozen and formalin-fixed paraffin-embedded human tissue samples.
TL;DR: Intrachip and interchip analyses demonstrated that the processes of miRNA extraction, labeling, and hybridization from both frozen and FFPE samples are highly reproducible and add little variation to the results; technical replicates showed high correlations with one another.
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Joint single cell DNA-seq and RNA-seq of gastric cancer cell lines reveals rules of in vitro evolution.
Noemi Andor,Billy T. Lau,Claudia Catalanotti,Anuja Sathe,Matthew Kubit,Jiamin Chen,Cristina Blaj,Athena M. Cherry,Charles D. Bangs,Susan M. Grimes,Carlos Suárez,Hanlee P. Ji +11 more
- 01 Jun 2020
TL;DR: A single- cell DNA sequencing approach was used to characterize the cellular diversity within nine gastric cancer cell lines and integrated this information with single-cell RNA sequencing and corroborated 88% of the clonal structure determined from single cell DNA analysis.
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