Jiajun Zhao
22 Papers
1 Citations
Jiajun Zhao is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 9 publications.
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Papers
Upregulation of WDR6 drives hepatic de novo lipogenesis in insulin resistance in mice.
Zhenyu Yao,Ying Gong,Wenbin Chen,Shanshan Shao,Yongfeng Song,Honglin Guo,Qihang Li,Sijin Liu,Ximing Wang,Zhenhai Zhang,Qian Wang,Yunyun Xu,Yingjie Wu,Qiang Wan,Xinya Zhao,Qiuhui Xuan,Dawei Wang,Xiaoyan Lin,Jiawen Xu,Jun Lu,Christopher G Proud,Xuemin Wang,Rui Yang,Lili Fu,Shaona Niu,Junjie Kong,Ling Gao,Tao Bo,Jiajun Zhao +28 more
TL;DR: WDR6 contributes to promoting hepatic de novo lipogenesis during insulin resistance by upregulation of fatty acid synthase, and the authors identify a small molecule to inhibit this effect of WDR6 and reduce hepatic steatosis.
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Association of complement components with the risk and severity of NAFLD: A systematic review and meta-analysis
Jianbo Zhao,Yafei Wu,Peng Lu,Xiaoqin Wu,Junming Han,Yingzhou Shi,Yue Liu,Yiping Cheng,Ling Gao,Jiajun Zhao,Zhen Wang,Xiude Fan +11 more
TL;DR: Wang et al. as discussed by the authors conducted a meta-analysis to evaluate the association of complement components with the risk and severity of NAFLD. But the relationship between complement components and the risk of nonalcoholic fatty liver disease (NAFLD) is inconsistent.
The effects of obesity and metabolic abnormalities on severe COVID-19-related outcomes after vaccination: A population-based study
Xiude Fan,Junming Han,Enfa Zhao,Jiansong Fang,Dawei Wang,Yiping Cheng,Yingzhou Shi,Zhen Wang,Zhenyu Yao,Peng-jun Lu,Qihang Li,Kyle L. Poulsen,Zhongshang Yuan,Yongfeng Song,Jiajun Zhao +14 more
TL;DR: In this article , the authors identify the modifiable risk factors that may affect the protective efficacy of vaccine use against the development of severe COVID-19 and thus to initiate early medical interventions.
10
Pathogenic mechanisms of osteogenesis imperfecta, evidence for classification
Hongjie Yu,Chang Ming Li,Huixiao Wu,Weibo Xia,Yanzhou Wang,Jiajun Zhao,Chao Xu +6 more
TL;DR: This study summarizes and classifies the pathogenic mechanisms of osteogenesis imperfecta, a connective tissue disorder, into four categories: type I collagen defects, bone mineralization disorders, osteoblast differentiation defects, and folding/cross-linking defects, providing a scientific basis for diagnosis and treatment.
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Beyond Body Weight: Diversified Presentation of MASLD in Lean, Overweight, and Obese Participants.
Xiude Fan,Yingzhou Shi,Junming Han,Yongfeng Song,Jiajun Zhao +4 more
TL;DR: This study redefines MASLD, introducing liver steatosis and cardiometabolic factors, and explores its manifestation in lean, overweight, and obese participants, challenging previous assumptions that obesity is the primary influence on fatty liver diseases.
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