Jiahao Wang
Fudan University
8 Papers
1 Citations
Jiahao Wang is an academic researcher from Fudan University. The author has contributed to research in topics: Tumor microenvironment & Pancreatic cancer. The author has an hindex of 5, co-authored 5 publications.
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Papers
Dual-mechanism based CTLs infiltration enhancement initiated by Nano-sapper potentiates immunotherapy against immune-excluded tumors.
Yukun Huang,Yu Chen,Songlei Zhou,Liang Chen,Jiahao Wang,Yuanyuan Pei,Minjun Xu,Jingxian Feng,Tianze Jiang,Kaifan Liang,Shanshan Liu,Qingxiang Song,Gan Jiang,Xiao Gu,Qian Zhang,Xiaoling Gao,Jun Chen +16 more
TL;DR: A dual-mechanism based CTLs infiltration enhancer, Nano-sapper, is reported, which can simultaneously reduce the physical obstacles in tumor microenvironment and recruiting C TLs to potentiate immunotherapy in IET.
Sequential delivery of nanoformulated α-mangostin and triptolide overcomes permeation obstacles and improves therapeutic effects in pancreatic cancer.
Jingxian Feng,Minjun Xu,Jiahao Wang,Songlei Zhou,Y. P. Liu,Shanshan Liu,Yukun Huang,Yu Chen,Liang Chen,Qingxiang Song,Jingru Gong,Huiping Lu,Xiaoling Gao,Jun Chen +13 more
TL;DR: Wang et al. as discussed by the authors developed a CAFs-targeting biodegradable polymer nanoparticle (CRE-NP) coated with CREKA peptide and loaded with TCM α-mangostin (α-M) to modulate tumor microenvironment by interfering of TGF-β/Smad signaling pathway.
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Metformin and Docosahexaenoic Acid Hybrid Micelles for Premetastatic Niche Modulation and Tumor Metastasis Suppression
Tianze Jiang,Liang Chen,Yukun Huang,Jiahao Wang,Minjun Xu,Songlei Zhou,Xiao Gu,Yu Chen,Kaifan Liang,Yuanyuan Pei,Qingxiang Song,Shanshan Liu,Fenfen Ma,Huiping Lu,Xiaoling Gao,Jun Chen +15 more
TL;DR: The findings here provide proof of concept that the modulation of the premetastatic niche with targeted anti-inflammatory agents provides a potent platform and a safe and clinical translational option for the suppression of tumor metastasis.
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Therapeutic effects and mechanisms of plant-derived natural compounds against intestinal mucositis
TL;DR: The present article aims at systematically discussing the recent progress of plant-derived natural compounds as promising treatments for intestinal mucositis, which have lately become potential candidates against enteric injury ascribed to the capacity to facilitate mucosal healing and anti-inflammatory effects.
Biguanide-anchored albumin-based nanoplatform inhibits epithelial-mesenchymal transition and reduces the stemness phenotype for metastatic cancer therapy.
Tianze Jiang,Jiahao Wang,Laozhi Xie,Songlei Zhou,Yukun Huang,Yu Chen,Xiaoling Gao,Wenze Xiao,Jun Chen +8 more
TL;DR: This study provides proof of concept that the biguanide-anchored albumin-based nanoplatform encapsulating PTX is a powerful, safe, and clinically translational strategy for the treatment of metastatic cancer.
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