Jiafan Chen
Sun Yat-sen University
11 Papers
17 Citations
Jiafan Chen is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 3, co-authored 4 publications.
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Papers
Ferroptosis: The Potential Target in Heart Failure with Preserved Ejection Fraction
TL;DR: This review explains the possible correlations between HFpEF and ferroptosis and provides a reliable theoretical basis for future studies on its mechanism.
Nuclear GAPDH is vital for hypoxia-induced hepatic stellate cell apoptosis and is indicative of aggressive hepatocellular carcinoma behavior
Yihang Gong,Baojia Zou,Siqi Peng,Peiping Li,Genglong Zhu,Jiafan Chen,Jianxu Chen,Xialei Liu,Wenying Zhou,Lei Ding,Y.-m. Chen,Linjuan Zeng,Baimeng Zhang,Chaonong Cai,Jian Li +14 more
TL;DR: Findings provide a novel mechanism underlying the involvement of intranuclear GAPDH in hypoxia-induced HSCs apoptosis and a correlation between nuclear GAPDh levels and the clinical prognosis, which may prompt the development of a novel therapeutic strategy for HCC.
The protective effect of inhibiting mitochondrial fission on the juvenile rat brain following PTZ kindling through inhibiting the BCL2L13/LC3 mitophagy pathway
Qiong Fang,Shaojuan Zheng,Qiaobin Chen,Lang Chen,Yating Yang,Ying Wang,Huixia Zhang,Jiafan Chen +7 more
TL;DR: Inhibition of mitochondrial fission could reduce seizure attacks, protect injured neurons, and improve cognition following PTZ-induced epilepsy by inhibiting mitochondrial autophagy mediated by the BCL2L13/LC3 mitophagy pathway.
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The impact of liver fibrosis on microvascular invasion and prognosis of hepatocellular carcinoma with a solitary nodule: a Surveillance, Epidemiology, and End Results (SEER) database analysis
En Lin,Baojia Zou,Guifang Zeng,Chaonong Cai,Peiping Li,Jiafan Chen,Decheng Li,Baimeng Zhang,Jian Li +8 more
TL;DR: Wang et al. as mentioned in this paper investigated the effects of liver fibrosis on microvascular invasion and prognosis in non-cirrhotic hepatocellular carcinoma (HCC) with a high recurrence.
Efficacy of Adjuvant Transarterial Chemoembolization after Radical Hepatectomy in Solitary Hepatocellular Carcinoma Patients: A Retrospective Study
Guifang Zeng,Baojia Zou,Yongliang Li,E. Lin,Xialei Liu,Peiping Li,Jiafan Chen,Baimeng Zhang,Yingbin Jia,Chaonong Cai,Jian Li +10 more
TL;DR: PA-TACE may not improve the long-term survival of SHCC patients, but may even potentially promote their postoperative tumor recurrence, especially for those with MVI-negative, tumor size ≤ 5 cm, and preoperative AFP < 400 ng/ml.
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