5 Papers
69 Citations
Jia-yu Duan is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Allele frequency & Genotype. The author has an hindex of 5, co-authored 5 publications.
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Papers
Systematic confirmation study of GWAS-identified genetic variants for Kawasaki disease in a Chinese population.
Jiao Lou,Rong Zhong,Na Shen,Xuzai Lu,Juntao Ke,Jia-yu Duan,Yan-qi Qi,Yu-jia Wang,Qing Zhang,Wei Wang,Fang-qi Gong,Xiaoping Miao +11 more
TL;DR: It is suggested that 4 GWAS-identified SNPs, rs2736340, rs4813003, rs3818298 and rs1801274, were nominally associated with KD risk in a Han Chinese population individually and jointly.
A genetic variant rs1801274 in FCGR2A as a potential risk marker for Kawasaki disease: a case-control study and meta-analysis.
Jia-yu Duan,Jiao Lou,Qing Zhang,Juntao Ke,Yan-qi Qi,Na Shen,Beibei Zhu,Rong Zhong,Zhenling Wang,Lifeng Liu,Jing Wu,Wei Wang,Fang-qi Gong,Xiaoping Miao +13 more
TL;DR: A meta-analysis of genome-wide association studies found rs1801274, a functional single nucleotide polymorphism in IgG receptor gene FCGR2A, was associated with increased risk of Kawasaki disease (KD), and confirmed that this SNP is significantly associated withincreased risk of KD.
The Roles of Ca2+/NFAT Signaling Genes in Kawasaki Disease: Single- and Multiple-Risk Genetic Variants
Wei Wang,Jiao Lou,Rong Zhong,Yan-qi Qi,Na Shen,Xuzai Lu,Yujia Wang,Qing Zhang,Li Zou,Jia-yu Duan,Juntao Ke,Xiaoping Miao,Fangqi Gong +12 more
TL;DR: It is implicates that single- and multiple-risk genetic variants in this pathway might contribute to KD susceptibility and further studies on more comprehensive single nucleotide polymorphisms, different ethnicities and larger sample sizes are warranted.
8p22-23-rs2254546 as a Susceptibility Locus for Kawasaki Disease: a Case-control Study and a Meta-analysis
Wei Wang,Jiao Lou,Xuzai Lu,Yan-qi Qi,Na Shen,Rong Zhong,Yu-jia Wang,Li Zou,Qing Zhang,Jia-yu Duan,Juntao Ke,Xiaoping Miao,Fang-qi Gong +12 more
TL;DR: An integrated meta-analysis revealed that the G allele was significantly associated with the increased KD risk without evidence of heterogeneity, suggesting that rs2254546 polymorphism might significantly contribute to the risk of KD.
A functional variant rs1820453 in YAP1 and breast cancer risk in Chinese population.
Wei Chen,Wei Wang,Beibei Zhu,Hui Guo,Yu Sun,Jie Ming,Na Shen,Zhi Li,Zhenling Wang,Lifeng Liu,Bingxi Cai,Jia-yu Duan,Jiaoyuan Li,Cheng Liu,Rong Zhong,Weiguo Hu,Tao Huang,Xiaoping Miao +17 more
TL;DR: The results from this study suggested that rs1820453 A>C change may affect the gene expression and contribute to the risk of developing BC in Chinese population though larger sample-size studies along with functional experiments were anticipated to warrant the results.
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