Jia Ming
Chinese Academy of Sciences
6 Papers
103 Citations
Jia Ming is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Conidiation & Aspergillus fumigatus. The author has an hindex of 4, co-authored 4 publications.
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Papers
O-Mannosyltransferase 1 in Aspergillus fumigatus (AfPmt1p) is crucial for cell wall integrity and conidium morphology, especially at an elevated temperature.
TL;DR: In this article, the PMT gene family of the human fungal pathogen Aspergillus fumigatus was identified and characterized, where only one member of each PMT subfamily, Afpmt1, AfPmt1p, AfPMt2, and AfPmt4, is present in A fumarigatus.
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Deletion of the msdS/AfmsdC gene induces abnormal polarity and septation in Aspergillus fumigatus
TL;DR: Results show that msdS is involved in polarity and septation in A. fumigatus, a filamentous fungi with an important role in the processing of mannose-containing glycans in eukaryotes.
Reduced expression of the O-mannosyltransferase 2 (AfPmt2) leads to deficient cell wall and abnormal polarity in Aspergillus fumigatus
TL;DR: The results suggest that Af pmt2 gene was required for growth and played a role distinct from that of the Afpmt1 in A. fumigatus and caused a failure of the actin re-arrangement.
miR-382 inhibits breast cancer progression and metastasis by affecting the M2 polarization of tumor-associated macrophages by targeting PGC-1α
TL;DR: The results of the present study suggest that miR-382 may alter the metabolic status of macrophages by targeting PGC-1α, thereby decreasing the proportion of TAMs with the M2 phenotype, and inhibiting the progression and metastasis of breast cancer.
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Characterization of the Aspergillus fumigatus phosphomannose isomerase Pmi1 and its impact on cell wall synthesis and morphogenesis
TL;DR: The results reveal that PMI activity is essential for viability and plays a central regulatory role in both cell wall synthesis and energy production in A. fumigatus.