Jesse B. Yoder
Johns Hopkins University School of Medicine
10 Papers
28 Citations
Jesse B. Yoder is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Calmodulin & Sodium channel. The author has an hindex of 6, co-authored 8 publications. Previous affiliations of Jesse B. Yoder include Johns Hopkins University & Roy J. and Lucille A. Carver College of Medicine.
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Papers
Regulation of the NaV1.5 cytoplasmic domain by calmodulin
Sandra B. Gabelli,Agedi N. Boto,Victoria Halperin Kuhns,Mario A. Bianchet,Federica Farinelli,Srinivas Aripirala,Jesse B. Yoder,Jean Jakoncic,Gordon F. Tomaselli,L. Mario Amzel +9 more
TL;DR: It is proposed that the structure reported here represents a non-inactivated state of the CTNav, i.e., the state that is poised for activation.
Calmodulin and Ca2+ control of voltage gated Na+ channels
TL;DR: The structures of the cytosolic portion of voltage activated sodium channels (CTNav) in complexes with calmodulin and other effectors in the presence and the absence of calcium provide information about the mechanisms by which these effectors regulate channel activity.
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Bilobal architecture is a requirement for calmodulin signaling to CaV1.3 channels.
Rahul Banerjee,Jesse B. Yoder,David T. Yue,L. Mario Amzel,Gordon F. Tomaselli,Sandra B. Gabelli,Manu Ben-Johny,Manu Ben-Johny +7 more
TL;DR: A unified scheme of CaV channel regulation by CaM now emerges, and the findings highlight the versatility of CaM to perform exquisite Ca2+ computations.
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Structural basis of cytoplasmic NaV1.5 and NaV1.4 regulation
Sara Nathan,Sandra B. Gabelli,Jesse B. Yoder,Lakshmi Srinivasan,Richard W. Aldrich,Gordon F. Tomaselli,Manu Ben-Johny,L. Mario Amzel +7 more
TL;DR: In this review, Nathan et al. discuss recent structural insights into the regulation of the Na+ channels NaV 1.5 and NaV1.4, facilitated by the combination of cryo-EM and x-ray crystallography data.
Development of high-affinity nanobodies specific for NaV1.4 and NaV1.5 voltage-gated sodium channel isoforms
Lakshmi Prasanna Srinivasan,Vanina Alzogaray,Dakshnamurthy Selvakumar,Sara Nathan,Jesse B. Yoder,Katharine M. Wright,Sebastián Klinke,Justin N. Nwafor,María S. Labanda,Fernando Alberto Goldbaum,Arne Schön,Ernesto Freire,Gordon F. Tomaselli,L. Mario Amzel,Manu Ben-Johny,Sandra B. Gabelli +15 more
TL;DR: In this paper , high-affinity anti-NaV nanobodies (Nbs), Nb17 and Nb82, were generated from a phage display library for high affinity to the C-terminal (CT) region of NaV1.4.
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