Jeroen Bakkers
Utrecht University
126 Papers
367 Citations
Jeroen Bakkers is an academic researcher from Utrecht University. The author has contributed to research in topics: Zebrafish & Biology. The author has an hindex of 43, co-authored 118 publications. Previous affiliations of Jeroen Bakkers include Leiden University & Royal Netherlands Academy of Arts and Sciences.
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Papers
•Journal Article
Abstract 1103: Integrin-linked Kinase and Laminin alpha 4 Mutations Cause Human Cardiomyopathy
Ralph Knöll,Ruben Postel,Ralph Krätzner,Gerrit Hennecke,Andrei M. Vacaru,Padmanabhan Vakeel,Gudrun Knöll,Katrin Schäfer,Erik Bos,Jeroen den Hertog,Peter J. Peters,Fredericus J.M. van Eeden,Jutta Schaper,Wolfgang Schaper,Gerd Hasenfuss,Heinz-Peter Schultheiss,Kenneth R. Chien,Jeroen Bakkers +17 more
TL;DR: Background - Dilated Cardiomyopathy (DCM) is a syndrome characterized by ventricular dilation, contractile dysfunction and symptoms of congestive heart failure.
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Lifting the cloche: Jeroen Bakkers interviews Didier Stainier.
TL;DR: Stainier and Bakkers as mentioned in this paper used the zebrafish model to study heart development and regeneration in the early stages of the development of the human heart and showed that it is a powerful model organism to investigate cardiac development, disease and regeneration.
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Single-cell profiling of transcriptome and histone modifications with EpiDamID
Franka J. Rang,Kim L. de Luca,Sandra S. de Vries,Christian Valdes-Quezada,Ellen Boele,Phong D. Nguyen,Isabel Guerreiro,Yuko Sato,Hiroshi Kimura,Jeroen Bakkers,Jeroen Bakkers,Jop Kind,Jop Kind +12 more
TL;DR: In this article, DamID was used to profile single-cell Polycomb occupancy in mouse embryoid bodies and provide evidence for hierarchical gene regulatory networks, and they further demonstrate the applicability of this method to in vivo systems by mapping H3K9me3 in early zebrafish embryogenesis and detect striking heterochromatic regions specifically in the notochord.
Twists and turns.
Emily S. Noël,Jeroen Bakkers +1 more
TL;DR: Computational modeling of the heart tube during development reveals the interplay between tissue asymmetry and growth that helps our hearts take shape as mentioned in this paper, which is a very interesting topic.