Jeremie Boucher
University of Gothenburg
73 Papers
361 Citations
Jeremie Boucher is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Adipose tissue & Adipocyte. The author has an hindex of 36, co-authored 63 publications. Previous affiliations of Jeremie Boucher include French Institute of Health and Medical Research & Max Planck Society.
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Papers
Insulin Receptor Signaling in Normal and Insulin-Resistant States
TL;DR: In the wake of the worldwide increase in type-2 diabetes, a major focus of research is understanding the signaling pathways impacting this disease, which are essential for development of new drugs to treat diabetes, metabolic syndrome, and their complications.
Apelin, a newly identified adipokine up-regulated by insulin and obesity
Jeremie Boucher,Bernard Masri,Danièle Daviaud,Stephane Gesta,Charlotte Guigné,Anne Mazzucotelli,Isabelle Castan-Laurell,Ivan Tack,Bernard Knibiehler,Christian Carpéné,Yves Audigier,Jean-Sébastien Saulnier-Blache,Philippe Valet +12 more
TL;DR: Apelin is identified as a novel adipocyte endocrine secretion and its potential link with obesity-associated variations of insulin sensitivity status is focused on and evidence that insulin exerts a direct control on apelin gene expression in adipocytes is provided.
Evidence for a role of developmental genes in the origin of obesity and body fat distribution
Stephane Gesta,Matthias Blüher,Yuji Yamamoto,Andrew W. Norris,Janin Berndt,Susan Kralisch,Jeremie Boucher,Choy Lewis,C. Ronald Kahn +8 more
TL;DR: Together, these data suggest that genetically programmed developmental differences in adipocytes and their precursors in different regions of the body play an important role in obesity, body fat distribution, and potential functional differences between internal and subcutaneous adipose tissue.
648
Apelin Stimulates Glucose Utilization in Normal and Obese Insulin-Resistant Mice
Cédric Dray,Cédric Dray,Claude Knauf,Claude Knauf,Danièle Daviaud,Danièle Daviaud,Aurélie Waget,Aurélie Waget,Jeremie Boucher,Jeremie Boucher,Marie Buléon,Marie Buléon,Patrice D. Cani,Camille Attané,Camille Attané,Charlotte Guigné,Charlotte Guigné,Christian Carpéné,Christian Carpéné,Rémy Burcelin,Rémy Burcelin,Isabelle Castan-Laurell,Isabelle Castan-Laurell,Philippe Valet,Philippe Valet +24 more
TL;DR: It is shown that in chow-fed mice, acute intravenous injection of apelin has a powerful glucose-lowering effect associated with enhanced glucose utilization in skeletal muscle and AT and could represent a promising target in the management of insulin resistance.
523
Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production
Enxuan Jing,Brice Emanuelli,Matthew D. Hirschey,Jeremie Boucher,Kevin Y. Lee,David B. Lombard,Eric Verdin,C. Ronald Kahn +7 more
TL;DR: Sirt3 plays an important role in diabetes through regulation of mitochondrial oxidation, reactive oxygen species production, and insulin resistance in skeletal muscle.
468