Jens M. Hohlfeld
Hannover Medical School
247 Papers
1.7K Citations
Jens M. Hohlfeld is an academic researcher from Hannover Medical School. The author has contributed to research in topics: Medicine & Bronchoalveolar lavage. The author has an hindex of 49, co-authored 234 publications. Previous affiliations of Jens M. Hohlfeld include Fraunhofer Society & Hochschule Hannover.
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Papers
A dual center study to compare breath volatile organic compounds from smokers and non-smokers with and without COPD.
A Gaida,Olaf Holz,Christoph Nell,Sven Schuchardt,Bianca Lavae-Mokhtari,L Kruse,U Boas,Jens Langejuergen,Maria Allers,Stefan Zimmermann,Claus Vogelmeier,AR Koczulla,Jens M. Hohlfeld +12 more
TL;DR: The results show that, for the utilization of breath VOCs for diagnosis and disease management of COPD, not only the known effects of smoking but also site specific differences need to be considered.
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Validation of an environmental exposure unit for controlled human inhalation studies with grass pollen in patients with seasonal allergic rhinitis.
Norbert Krug,H. Loedding,Jens M. Hohlfeld,M. Larbig,A. Buckendahl,Philipp Badorrek,H. Geldmacher,W. Behnke,Wilhelm Dunkhorst,Horst Windt,Birgit Luettig,Wolfgang Koch +11 more
TL;DR: There is an increasing need for allergen inhalation systems to perform basic clinical research and test anti‐allergic drugs under well‐controlled conditions, which requires stability of environmental conditions like temperature and humidity, as well as allergenic concentration and reproducible induction of allergic symptoms.
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Stratification of asthma phenotypes by airway proteomic signatures
James P.R. Schofield,Dominic Burg,Ben Nicholas,Fabio Strazzeri,Joost Brandsma,Doroteya Staykova,Caterina Folisi,Aruna T. Bansal,Yang Xian,Yike Guo,Anthony Rowe,Julie Corfield,Susan J. Wilson,Jonathan Ward,René Lutter,Dominick E. Shaw,Per Bakke,Massimo Caruso,Sven-Erik Dahlén,Stephen J. Fowler,Ildiko Horvath,Peter H. Howarth,Norbert Krug,Paolo Montuschi,Marek Sanak,Thomas Sandström,Kai Sun,Ioannis Pandis,John H. Riley,Charles Auffray,Bertrand De Meulder,Diane Lefaudeux,Ana R. Sousa,Ian M. Adcock,Kian Fan Chung,Peter J. Sterk,Paul Skipp,Ratko Djukanovic,H. Ahmed,David B. Allen,P. Badorrek,Stephane Ballereau,F. Baribaud,Alun Bedding,Annelie F. Behndig,A. Berglind,A. Berton,Jeanette Bigler,Michael Boedigheimer,Klaus Bønnelykke,Paul Brinkman,Andrew Bush,Davide Campagna,Carmen Casaulta,Amphun Chaiboonchoe,T. Davison,B. De Meulder,Ingrid Delin,Patrick Dennison,P. Dodson,L. El Hadjam,D. Erzen,C. Faulenbach,K. Fichtner,Neil Fitch,Elena Formaggio,Martina Gahlemann,Gabriella Galffy,D. Garissi,T. Garret,J. Gent,E. Guillmant-Farry,Elisabeth Henriksson,Uruj Hoda,Jens M. Hohlfeld,X. Hu,Alan L. James,K. Johnson,N. Jullian,G. Kerry,M. Klüglich,Richard G. Knowles,Jon R Konradsen,Kosmas Kretsos,L. Krueger,Ann-Sofie Lantz,Christopher Larminie,Philipp Latzin,D. Lefaudeux,Nathanaël Lemonnier,L.A. Lowe,R. Lutter,Alexander Manta,Alexander Mazein,L. McEvoy,Andrew Menzies-Gow,N. Mores,Clare S. Murray,K. Nething,U. Nihlén,Robert Niven,Björn Nordlund,S. Nsubuga,Johann Pellet,Christophe Pison,G. Praticò,M. Puig Valls,K. Riemann,J.P. Rocha,Christos Rossios,G. Santini,Mansoor Saqi,S. Scott,N. Sehgal,Anna Selby,P. Söderman,A. Sogbesan,F. Spycher,S. Stephan,Jakob Stokholm,M. Sunther,M. Szentkereszty,L. Tamasi,Kamran Tariq,Salvatore Valente,W.M. van Aalderen,C. M. van Drunen,J. Van Eyll,Aashish Vyas,Wen Yu,Wilhelm Zetterquist,Zaraquiza Zolkipli,A.H. Zwinderman +132 more
TL;DR: This study provides further stratification of asthma currently classified based on quantification of granulocytic inflammation and provided additional insight into their underlying mechanisms, which could become targets for novel therapies.
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Activation of group 2 innate lymphoid cells after allergen challenge in asthmatic patients.
Carla Winkler,Thomas Hochdörfer,Elisabeth Israelsson,Annemarie Hasselberg,Anders Cavallin,Kristofer Thörn,Daniel Muthas,Shervin Shojaee,Katrin Lüer,Meike Müller,Jenny Mjösberg,Outi Vaarala,Jens M. Hohlfeld,Katerina Pardali +13 more
TL;DR: ILC2s accumulate at the site of allergic inflammation and are recruited from the blood, and their transcriptional and functional activation pattern promotes type 2 inflammation.
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Effect of Indacaterol/Glycopyrronium on Pulmonary Perfusion and Ventilation in Hyperinflated Patients with Chronic Obstructive Pulmonary Disease (CLAIM). A Double-Blind, Randomized, Crossover Trial.
Jens Vogel-Claussen,Christian-Olaf Schönfeld,Till F. Kaireit,Andreas Voskrebenzev,Christoph Czerner,Julius Renne,Hanns-Christian Tillmann,Korbinian Berschneider,Simone Hiltl,Johann Bauersachs,Tobias Welte,Jens M. Hohlfeld,Jens M. Hohlfeld +12 more
TL;DR: Pupil microvascular blood flow is reduced in chronic obstructive pulmonary disease (COPD) and regional ventilation is improved in patients with COPD with hyperinflation using magnetic resonance imaging (MRI).
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