This is the first description of a secondary mandibular overgrowth due to condylar misregulation in a congenitally undergrown mandible. This case of unilateral hemifacial microsomia proves the postulated existence (Mandibular Growth Anomalies: Terminology, Aetiology, Diagnosis, Treatment, 20

New clinical-based evidence for the existence of 2 growth regulators in mandibular condyles: hemimandibular elongation in hemifacial microsomia mandible.

Mandibular growth and tooth eruption after localized x-radiation.

The use of bone-seeking radiopharmaceutical uptake (BSRU) as an indicator of periodontal disease activity was assessed in untreated beagles with naturally occurring periodontal disease, and in beagles treated with the non-steroidal anti-inflammatory drug, flurbiprofen. In untreated beagles, a single uptake measurement was indicative of the rate of bone loss subsequently determined by sequential radiographs. Beagles treated with flurbiprofen demonstrated a significant decrease in rate of bone loss and a corresponding decrease in BSRU. Transfer of this technology to untreated human subjects with moderate to severe periodontal disease also showed a positive correlation between a single measurement of BSRU and the rate of bone loss determined from sequential radiographs. Analysis of these data shows that a single BSRU examination may be indicative of periodontal disease activity.

Nuclear medicine techniques for the detection of active alveolar bone loss.

Imaging forms an integral component for diagnosis of dental and in specific periodontal diseases. To date, intra-oral radiographic techniques are the main non-invasive diagnostic aids for the detection and assessment of internal changes in mineralized periodontal tissues like alveolar bone. These analog radiographic techniques suffer from inherent limitations like: Two dimensional projection, magnification, distortion, superimposition and misrepresentation of anatomic structures. The evolution of novel imaging modalities, namely cone beam computed tomography, tuned aperture CT empowered dental researchers to visualize the periodontium three dimensionally. This improves interpretation of structural and biophysical changes, ensures densitometric assessments of dentoalveolar structures including variations in alveolar bone density, and peri-implant bone healing more precisely. This detailed review, highlights current leading edge concepts, envisions a wide range of imaging modalities which pave the way for better understanding and early intervention of periodontal diseases.

Choice of diagnostic and therapeutic imaging in periodontics and implantology

99mTc-Medronate uptake in the temporomandibular joints of young rats treated with a mandibular hyperpropulsor*

Uptake of a bone-seeking radiopharmaceutical is correlated with growth changes in the rat mandible. Uptake was highest in newborn rats, decreasing with increasing age.

Bone-seeking radiopharmaceutical uptake as an indicator of mandibular growth in rats.

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Bone-seeking radiopharmaceutical uptake as an indicator of mandibular growth in rats.