Jee Yon Lee
University of California, Davis
8 Papers
15 Citations
Jee Yon Lee is an academic researcher from University of California, Davis. The author has contributed to research in topics: Colitis & Dysbiosis. The author has an hindex of 3, co-authored 8 publications. Previous affiliations of Jee Yon Lee include Yonsei University.
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Papers
High-Fat Diet and Antibiotics Cooperatively Impair Mitochondrial Bioenergetics to Trigger Dysbiosis that Exacerbates Pre-inflammatory Bowel Disease
Jee Yon Lee,Jee Yon Lee,Stephanie A. Cevallos,Mariana X. Byndloss,Connor R. Tiffany,Erin E. Olsan,Brian P. Butler,Briana M. Young,Andrew W.L. Rogers,Henry Nguyen,Kyong-Chol Kim,Sang-Woon Choi,Eunsoo Bae,Je Hee Lee,Ui Gi Min,Duk Chul Lee,Andreas J. Bäumler +16 more
TL;DR: As with patients, mice with pre-IBD exhibited notable expansions of Enterobacteriaceae that exacerbated low-grade mucosal inflammation, suggesting that remediating dysbiosis can alleviate inflammation.
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5-Aminosalicylic Acid Ameliorates Colitis and Checks Dysbiotic Escherichia coli Expansion by Activating PPAR-γ Signaling in the Intestinal Epithelium
Stephanie A. Cevallos,Jee Yon Lee,Eric M. Velazquez,Nora J. Foegeding,Catherine D. Shelton,Connor R. Tiffany,Beau H. Parry,Annica R. Stull-Lane,Erin E. Olsan,Hannah P. Savage,Henry Nguyen,Star S. Ghanaat,Austin J. Byndloss,Ilechukwu O. Agu,Renée M. Tsolis,Mariana X. Byndloss,Andreas J. Bäumler +16 more
TL;DR: In this paper, 5-aminosalicylic acid (5-ASA) was shown to improve colitis in dextran sulfate sodium (DSS)-treated mice by activating PPAR-γ signaling in the intestinal epithelium.
Increased Epithelial Oxygenation Links Colitis to an Expansion of Tumorigenic Bacteria.
Stephanie A. Cevallos,Jee Yon Lee,Connor R. Tiffany,Austin J. Byndloss,Luana Johnston,Mariana X. Byndloss,Andreas J. Bäumler +6 more
TL;DR: It is concluded that increased epithelial oxygenation in the colon is associated with an expansion of a prooncogenic driver species, thereby increasing the cancer-inducing activity of the microbiota.
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The metabolic footprint of Clostridia and Erysipelotrichia reveals their role in depleting sugar alcohols in the cecum.
Connor R. Tiffany,Jee Yon Lee,Andrew W.L. Rogers,Erin E. Olsan,Erin E. Olsan,Pavel Morales,Franziska Faber,Franziska Faber,Andreas J. Bäumler +8 more
TL;DR: In this paper, the authors combined microbial profiling with an un-targeted metabolomics approach to determine whether depletion of small metabolites in the cecum of mice correlated with the presence of specific bacterial taxa.
The longitudinal and cross-sectional heterogeneity of the intestinal microbiota.
TL;DR: In this paper, a review of the host factors involved in generating longitudinal and cross-sectional microbiota heterogeneity helps define physiological states that are characteristic of or appropriate to a homeostatic microbiome.
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