Jean-Pierre Pelletier
Université de Montréal
375 Papers
2.4K Citations
Jean-Pierre Pelletier is an academic researcher from Université de Montréal. The author has contributed to research in topics: Osteoarthritis & Medicine. The author has an hindex of 79, co-authored 347 publications.
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Papers
Oral treatment with PD-0200347, an α2δ ligand, reduces the development of experimental osteoarthritis by inhibiting the chondrocytes metalloproteases and inducible nitric oxide synthase gene expression and synthesis
C. Boileau,Johanne Martel-Pelletier,J. Brunet,Ginette Tardif,Denis J. Schrier,Craig M. Flory,M. Boily,Jean-Pierre Pelletier +7 more
TL;DR: The efficacy of PD-0200347 at reducing the progression of cartilage structural changes in an OA dog model was demonstrated and it showed that this effect is linked to the inhibition, at the transcriptional level, of the major pathophysiological mediators.
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The Recently Discovered Collagenase-3: A Key Role in Osteoarthritis
Johanne Martel Pelletier,Jean-Pierre Pelletier +1 more
- 01 Jan 1999
TL;DR: Data from the laboratory is summarized which suggests that, in addition to collagenase-1, collagen enzyme-3 is a key contributing factor in cartilage collagen degradation during the OA process.
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Risk factors associated with the occurrence of total knee arthroplasty in patients with knee osteoarthritis: a nested case–control study
Jean-Pierre Pelletier,Marc Dorais,Patrice Paiement,Jean-Pierre Raynauld,Johanne Martel-Pelletier +4 more
TL;DR: Worsening of valgus alignment, cartilage volume loss in the lateral compartment, BMLs and older injuries are important risk factors in women, while medial compartment cartilage loss and meniscal extrusion are in men.
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The relationship between knee loading during gait and cartilage thickness in nontraumatic and posttraumatic knee osteoarthritis.
A. Teoli,Melissa Cloutier-Gendron,Shirley Y K Ho,Susan Gu,Jean-Pierre Pelletier,Johanne Martel-Pelletier,Shawn M. Robbins +6 more
TL;DR: In this article, the authors examined the relationship between external knee moments during gait and tibio-femoral cartilage thickness in patients with nontraumatic and posttraumatic knee osteoarthritis.
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