Jean-Pierre Pelletier

TL;DR: The newly developed fully automated MRI based BML assessment technology not only detects the absence/ presence of these pathological signals in the osteoarthritic human knee, but also provides accurate quantitative assessment of BMLs in the global knee and knee regions.

TL;DR: Differences in interpretation of the evidence base and the conclusions derived from the recent guidelines for the management of knee osteoarthritis are highlighted and it is tried to understand where they derive from, proposing an evidence-based interpretation.

TL;DR: It is reported that NSAIDs, such as aceclofenac and dicl ofenac, can significantly decrease the synthesis of three major factors, PGE2, IL-1β and TNF-α, in joint articular tissues.