Jean-Charles Fruchart
Pasteur Institute
479 Papers
7.4K Citations
Jean-Charles Fruchart is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Apolipoprotein B & Lipoprotein. The author has an hindex of 94, co-authored 477 publications. Previous affiliations of Jean-Charles Fruchart include university of lille & Université de Montréal.
Chat about Author
Papers
Antibodies of predetermined specificity to apolipoprotein C-II elicited with a synthetic peptide. Characterization and use for immunoassays.
C. Delpierre,Catherine Fievet,V. Equagoo,Hafid Mezdour,C Cachera,Jean-Claude Gesquiere,André Tartar,Jean-Charles Fruchart +7 more
TL;DR: The antibodies proved to be as suitable as conventional anti-protein antibodies in an immunoenzymometric assay and, moreover, were able to develop 'rockets' in an electroimmunoassay.
3
•Journal Article
Lack of relationship between Lp(a) particle levels and albumin excretion rate in type 1 diabetic patients.
TL;DR: The data provide no evidence of a specific contribution of Lp(a) particles to the increased morbidity and mortality from cardiovascular disease observed among patients with nephropathy.
3
Régulation transcriptionnelle du métabolisme du cholestérol
TL;DR: The identification of sterol-activated nuclear receptors opens up a whole new area in the lipid and endocrinology research field and will undoubtedly contribute to find new therapeutic ways in the treatment of metabolic disorders linked to an abberated cholesterol metabolism.
3
Thrombin cleavage of apolipoprotein Bh of rabbit LDL: structural comparisons with human apolipoprotein B-100.
TL;DR: Identification of the thrombolytic fragments of the rabbit apoB have afforded the opportunity to compare the structures of both ApoB species, and in both species, a primary and secondary thrombin cleavage occur, but the size of the fragments produced is very different between the two species.
3