Jean-Charles Fruchart
Pasteur Institute
479 Papers
7.4K Citations
Jean-Charles Fruchart is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Apolipoprotein B & Lipoprotein. The author has an hindex of 94, co-authored 477 publications. Previous affiliations of Jean-Charles Fruchart include university of lille & Université de Montréal.
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Papers
Interstitial fluid apolipoprotein A-II : an association with the occurrence of myocardial infarction
TL;DR: The measurement of apo A-II in interstitial fluid increased the level of prediction of MI over the information provided by the plasma parameters, raising the possibility thatInterstitial fluid apo B-II levels may be associated with the occurrence of MI.
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Rapid sodium dodecyl sulfat/polyacrylamide gel electrophoresis of urinary proteins.
TL;DR: This procedure for the convenient separation of proteins by sodium dodecyl sulfate/polyacrylamide gel electrophoresis of urine from cases of renal disease seems to be valuable for investigation of proteinuria.
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In Vivo Glucosylated LpA-I Subfraction Evidence for Structural and Functional Alterations
B. Igau,Graciela Castro,Véronique Clavey,Christian Slomianny,Régis Bresson,Pierre Drouin,Jean-Charles Fruchart,Catherine Fievet +7 more
TL;DR: Cell culture data suggest that nonenzymatic glycosylation occurring on apo A-I can modify lipoprotein function, since it results in a decreased binding of GLpA-I to HeLa cells and impaired cholesterol efflux from Fu5AH rat hepatoma cells.
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Enzyme-linked immunosorbent assay for serum amyloid A apolipoprotein with use of specific antibodies against synthetic peptides
Rachid Saile,C. Delpierre,P. Puchois,G. Hocke,C Cachera,Jean-Claude Gesquiere,A Steinmetz,André Tartar,Jean-Charles Fruchart +8 more
TL;DR: A noncompetitive enzyme-linked immunosorbent assay for amyloid A apolipoprotein in human serum (apo SAA) in which specific antibodies against synthetic peptides are used and results correlate well with those by a nephelometric method in which polyclonal antibodies are used.
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Antioxidant Therapy and Uptake of Human Oxidized LDL by Macrophages
TL;DR: In vitro, vitamin E, a free radical scavenger, suppresses LDL modification induced by endothelial cells or cupric solution, and long-term antioxidant treatment reduces, in WHHL rabbits, LDL uptake in atherosclerotic areas.
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