Jean-Baptiste Woillard
University of Limoges
123 Papers
171 Citations
Jean-Baptiste Woillard is an academic researcher from University of Limoges. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 20, co-authored 84 publications. Previous affiliations of Jean-Baptiste Woillard include French Institute of Health and Medical Research.
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Papers
Can the Area Under the Curve/Trough Level Ratio Be Used to Optimize Tacrolimus Individual Dose Adjustment?
TL;DR: In this article , the intraindividual variability of the area under the curve (AUC)/predose concentration (C0) ratio in comparison with that of AUC, C0, AUC/dose, and C0/dose.
Mycophenolic acid area under the concentration-time curve is associated with therapeutic response in childhood-onset lupus nephritis.
Astrid Godron-Dubrasquet,Jean-Baptiste Woillard,Stéphane Decramer,Marc Fila,Vincent Guigonis,Stéphanie Tellier,Denis Morin,Maud Sordet,F Saint-marcoux,Jérôme Harambat +9 more
TL;DR: MPA-AUC is associated with better response rate and may be considered as a target value in pediatric lupus nephritis and leading to individualized dosing may improve efficacy of MMF.
Towards therapeutic drug monitoring of everolimus in cancer? Results of an exploratory study of exposure-effect relationship.
Marine Deppenweiler,Sabrina Falkowski,Franck Saint-Marcoux,Caroline Monchaud,Nicolas Picard,Marie-Laure Laroche,Nicole Tubiana-Mathieu,Laurence Venat-Bouvet,Pierre Marquet,Jean-Baptiste Woillard +9 more
TL;DR: The results are in favour of TDM for everolimus in oncology especially with a large number of patients and more homogeneous types of cancer.
Population pharmacokinetic model and Bayesian estimator for two tacrolimus formulations--twice daily Prograf and once daily Advagraf
Jean-Baptiste Woillard,Brenda C. M. de Winter,Nassim Kamar,Pierre Marquet,Pierre Marquet,Lionel Rostaing,Annick Rousseau,Annick Rousseau +7 more
TL;DR: The single Bayesian estimator developed yields good predictive performance for estimation of individual tacrolimus inter-dose AUC in Prograf and Advagraf treated patients and is suitable for clinical practice.
A Time-Dependent Model Describes Methotrexate Elimination and Supports Dynamic Modification of MRP2/ABCC2 Activity.
Jean-Baptiste Woillard,Jean Debord,Isabelle Benz-de-Bretagne,Franck Saint-Marcoux,Pascal Turlure,Stephane Girault,Julie Abraham,Sylvain Choquet,Pierre Marquet,Chantal Barin-Le Guellec +9 more
TL;DR: Self-inhibition of the MRP2-dependent secretion of MTX is a plausible explanation for the time-dependent PKs of this drug.