Je-Jung Lee
Chonnam National University
411 Papers
1.9K Citations
Je-Jung Lee is an academic researcher from Chonnam National University. The author has contributed to research in topics: Medicine & Multiple myeloma. The author has an hindex of 38, co-authored 374 publications.
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Papers
•Journal Article
Interleukin-21 increases direct cytotoxicity and IFN-γ production of ex vivo expanded NK cells towards breast cancer cells
Young-Ki Park,Dong-Jun Shin,Duck Cho,Sang-Ki Kim,Je-Jung Lee,Myung-Geun Shin,Dong-Wook Ryang,Ji-Shin Lee,Min Ho Park,Jung Han Yoon,Young Jong Jegal +10 more
TL;DR: IL-21 significantly enhances the cytolytic activity and IFN-γ production of ex vivo expanded NK cells in response to trastuzumab-coated breast cancer cells.
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Ex vivo expansion of canine cytotoxic large granular lymphocytes exhibiting characteristics of natural killer cells
Dong-Jun Shin,Ji-Yun Park,Youn-Young Jang,Je-Jung Lee,Youn-Kyung Lee,Myung-Geun Shin,Ji-Youn Jung,William E. Carson,Duck Cho,Sang-Ki Kim,Sang-Ki Kim +10 more
TL;DR: This study selectively expanded the canine cytotoxic large granular lymphocytes (CLGLs) that exhibit morphologic, genetic, and functional characteristics of NK cells from normal donor PBMCs to suggest that these CLGLs represent a population of canine NK cells.
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Response to high-dose intravenous immune globulin as a valuable factor predicting the effect of splenectomy in chronic idiopathic thrombocytopenic purpura patients
Chul Won Choi,Byung Soo Kim,Jae Hong Seo,Sang Won Shin,Yeul Hong Kim,Jun Suk Kim,Sang Kyun Sohn,Jae Seok Kim,Dong Gun Shin,Hun Mo Ryoo,Kyung Hee Lee,Je-Jung Lee,Ik Joo Chung,Hyeoung Joon Kim,Jae Yong Kwak,Chang Yeol Yim,Jin Seok Ahn,Jung Ae Lee,Young Suk Park +18 more
TL;DR: The results indicate that the response to high‐dose IVIG could be a valuable factor predicting the sustained response to splenectomy in chronic ITP patients.
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Naïve CD8(+) T cell derived tumor-specific cytotoxic effectors as a potential remedy for overcoming TGF-β immunosuppression in the tumor microenvironment.
Hong Hanh Nguyen,Therasa Kim,Sang Yun Song,Somang Park,Hyang Hee Cho,Sung-Hoon Jung,Jae-Sook Ahn,Hyeoung-Joon Kim,Je-Jung Lee,Hee-Ok Kim,Jaeho Cho,Deok-Hwan Yang +11 more
TL;DR: Of CD8+ T cell pools activated to tumor-specific CTLs, naïve cell generated effectors possessed the most potent cytotoxic activity, validating implications for use in rational design of adoptive immunotherapy.
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Comprehensive evaluation of the revised international staging system in multiple myeloma patients treated with novel agents as a primary therapy.
Hyungwoo Cho,Dok Hyun Yoon,Jung Bok Lee,Sung-Yong Kim,Joon Ho Moon,Young Rok Do,Jae Hoon Lee,Yong Park,Ho Sup Lee,Hyeon Seok Eom,Ho-Jin Shin,Chang-Ki Min,Jin Seok Kim,Jae-Cheol Jo,Hye Jin Kang,Yeung-Chul Mun,Won Sik Lee,Je-Jung Lee,Cheolwon Suh,Kihyun Kim +19 more
TL;DR: The R‐ISS performs well and has significantly better discriminative power than the ISS in MM patients treated with novel agents as a primary therapy, however, it does not better reclassify patients from the ISS, suggesting that there is still room to improve the staging system.
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