Jayson X. Chen
Rutgers University
13 Papers
43 Citations
Jayson X. Chen is an academic researcher from Rutgers University. The author has contributed to research in topics: Colitis & Cancer. The author has an hindex of 7, co-authored 13 publications.
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Papers
Gene regulation mediated by microRNAs in response to green tea polyphenol EGCG in mouse lung cancer
Hong-Ning Zhou,Jayson X. Chen,Chung S. Yang,Mary Qu Yang,Mary Qu Yang,Youping Deng,Hong Tian Wang +6 more
TL;DR: These results demonstrate that the miRNA-mediated regulation is actively involved in the major aspects of the anti-cancer activity of EGCG in vivo.
β-Sitosterol and stigmasterol ameliorate dextran sulfate sodium-induced colitis in mice fed a high fat Western-style diet
Simin Feng,Simin Feng,Simin Feng,Zhuqing Dai,Zhuqing Dai,Anna Liu,Hong Wang,Jayson X. Chen,Zisheng Luo,Chung S. Yang +9 more
TL;DR: Dietary intake of stigmasterol and β-sitosterol ameliorates colitis in male mice fed a high fat Western-style diet, suggesting that dietary intake of these phytosterols is beneficial for colitis.
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Effects of Tea Catechins on Cancer Signaling Pathways
TL;DR: This chapter reviews the basic redox properties of tea catechins, their binding to key enzymes and signal transduction proteins, and other mechanisms that lead to suppression of cell proliferation, increased apoptosis, and inhibition of angiogenesis.
NNK-induced DNA methyltransferase 1 in lung tumorigenesis in A/J mice and inhibitory effects of (-)-epigallocatechin-3-gallate.
Huanyu Jin,Jayson X. Chen,Hong Wang,Gary Lu,Anna Liu,Guangxun Li,Shuiping Tu,Yong Lin,Chung S. Yang +8 more
TL;DR: It is found that administration of NNK to A/J mice caused elevation of DNMT1 in bronchial epithelial cells at Days 1, 3, and 14 after NNK treatment, andDNMT1 elevation at Day 1 was accompanied by an increase in phospho-histone H2AX (γ-H2AX) and phospho -AKT (p-AKT).
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δ- and γ-tocopherols inhibit phIP/DSS-induced colon carcinogenesis by protection against early cellular and DNA damages.
Jayson X. Chen,Anna Liu,Mao-Jung Lee,Hong Wang,Siyuan Yu,Eric Chi,Kenneth R. Reuhl,Nanjoo Suh,Chung S. Yang +8 more
TL;DR: Results suggest that the inhibitory effect of δ‐T against colon carcinogenesis is mainly due to protection against early cellular and DNA damages caused by PhIP, and that α‐T was found to be ineffective in inhibiting colon tumors and less effective in attenuating the molecular changes.