Jayant Kumar
4 Papers
Jayant Kumar is an academic researcher. The author has contributed to research in topics: Medicine & Epoetin alfa. The author has an hindex of 2, co-authored 3 publications.
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Papers
A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Nalbuphine ER Tablets for Uremic Pruritus
Vandana S Mathur,Jayant Kumar,Paul W Crawford,Howard Hait,Thomas Sciascia,Tr Study Investigators +5 more
TL;DR: In this largest-to-date randomized controlled trial in uremic pruritus, NAL 120 durably and significantly reduced the itching intensity among hemodialysis patients.
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A Comparison of the Safety and Efficacy of HX575 (Epoetin Alfa Proposed Biosimilar) with Epoetin Alfa in Patients with End-Stage Renal Disease.
Matthew R. Weir,Pablo E. Pergola,Rajiv Agarwal,Jeffrey C. Fink,Nelson Kopyt,Ajay K. Singh,Jayant Kumar,Susanne Schmitt,Gregor Schaffar,Anita Rudy,James McKay,Radmila Kanceva +11 more
TL;DR: SC HX575 in dialysis patients with renal anemia was therapeutically equivalent to the reference medicine in terms of maintaining stable Hb levels and safety, and neither method of treatment led to the development of neutralizing, clinically relevant antibodies.
A Comparison of the Safety and Efficacy of HX575 (Epoetin Alfa Proposed Biosimilar) with Epoetin Alfa in Patients with End-Stage Renal Disease
Matthew R. Weir,Pablo E. Pergola,Rajiv Agarwal,Jeffrey C. Fink,Nelson Kopyt,Ajay K. Singh,Jayant Kumar,Susanne Schmitt,Gregor Schaffar,Anita Rudy,James McKay,Radmila Kanceva +11 more
- 01 Nov 2017
TL;DR: In this paper, the clinical equivalence of HX575 with the US-licensed reference epoetin alfa (Epogen®/Procrit®, Amgen/Janssen) following subcutaneous (SC) administration in dialysis patients with CKD-related anemia was assessed.
Dual endothelin antagonist aprocitentan for resistant hypertension (PRECISION): a multicentre, blinded, randomised, parallel-group, phase 3 trial
Markus P. Schlaich,Marc Bellet,Michael A. Weber,Parisa Danaietash,George L. Bakris,John M. Flack,Roland F. Dreier,M. Sassi-Sayadi,Lloyd Haskell,Krzysztof Narkiewicz,Ji-Guang Wang,Christopher M. Reid,Ivor Katz,Andrew E. Ajani,Sinjini Biswas,Murray D. Esler,Grahame J Elder,Simon D. Roger,David Colquhoun,John D. Mooney,G. De Backer,Alexandre Persu,Martin Chaumont,Jean-Marie Krzesinski,Thomas Vanabsche,Ginette Girard,L Pliamm,Ernesto L. Schiffrin,Fatima S. Merali,George K. Dresser,Michel Vallée,Shivinder S. Jolly,Stephen Chow,Ji-Gwang Wang,Jianjun Mu,Jing Yu,Hong Yuan,Yingqing Feng,Xin Zhang,Jianhong Xie,Ling Lin,Miroslav Souček,J Widimsky,Renata Cifkova,Jan Václavík,Martin Ullrych,M Lukac,Ivan Rychlik,Thomas G. Lauridsen,Ilkka Kantola,Jyrki Taurio,Olavi Ukkola,Olivier Ormezzano,Philippe Gosse,Michel Azizi,Pierre-Yves Courand,Pascal Delsart,Jean-Michel Tartière,Felix Mahfoud,Roland E. Schmieder,Johannes Stegbauer,Philipp Lurz,Michael Koziolek,Christian Otte,Nicole Toursarkissian,Constantinos Tsioufis,K. Kyfnidis,Athanasios J. Manolis,Sotirios Patsilinakos,Pantelis Zebekakis,Apostolos Karavidas,Páll Dénes,Katalin Bezzegh,Marianna Zsom,László Kovács,Yehonatan Sharabi,Mazen Elias,Ivetta Sukholutsky,Chaim Yosefy,I. Kenis,Shaul Atar,Massimo Volpe,Muiesan Maria Lorenza,Stefano Taddei,Guido Grassi,Franco Veglio,Jung Woo Son,Jang Young Kim,Joong-Il Park,Chang Hoon Lee,Hae Young Lee,Rasa Raugaliene,Jolanta E. Marcinkeviciene,R. Kavaliauskiene,Jaap Deinum,Abraham A. Kroon,Bert Jan H. van den Born,Andrzej Januszewicz,Andrzej Tykarski,J. Walczewska,Zbigniew Gaciong,Andrzej Wiecek,Marzena Chrostowska,Andrzej Kleinrok,Jan Krekora,Grzegorz Kania,Anna Podrazka-Szczepaniak,Cezary Goławski,Maciej Podziewski,Barbara Kaczmarek,G.A. Skoczylas,Andrzej Wilkolaski,I. Woźniak,Marzena Janik-Palazzolo,Barbara Rewerska,Alexandra Konradi,Yu. V. Shvarts,T B Pecherina,Konstantin Nikolaev,Gapon Liudmila,O. Orlikova,Viktor Mordovin,N. V. Petrochenkova,G. Kamalov,E. D. Kosmacheva,V. V. Tyrenko,V. I. Gorbunov,A. G. Obrezan,Tatiana Vyacheslavovna Supryadkina,Irina A Ler,O.G. Kotenko,Anatoly Kuzin,Fernando Martinez,Josep Redon,Anna Oliveras,Luis Beltran Romero,V. B. Shatylo,L Rudenko,Andrii Bazylevych,Yu.Yu. Rudyk,Oleksandr Karpenko,Mykola Stanislavchuk,Vira Tseluyko,Mykola Kushnir,E. Asanov,Yuriy Sirenko,Andriy Yagensky,David A. Collier,Pankaj Gupta,David J. Webb,Mary MacLeod,James M McLay,Aaron Peace,Samir Arora,Patricia Michelle Buchanan,Robert Sean Harris,Ronald G DeGarmo,Mario Guillen,Adam D. Karns,Joel M. Neutel,Yogesh Paliwal,Karl William Pettis,Phillip D Toth,Jeffrey M. Wayne,Bain Butcher,Philip Diller,Suzanne Oparil,D. Calhoun,Donald Brautigam,Jesse Matthew Goldman,Arash Rashidi,Nabeel Aslam,William Haley,Nabil Andrawis,Brian Lang,Randy L. Miller,James Powell,Robert Dewhurst,James Pritchard,D. Khanna,Dennis Tang,Nashwa Gabra,Jean-Ho Park,Conigliaro Jones,Cranford L. Scott,Blanca Alicia Luna,Murtaza Mussaji,Ravi Bhagwat,Michael Bauer,J M McGinty,R. Nambiar,Renee Sangrigoli,William R. Davis,William Eaves,Frank McGrew,Ahmed Hamdy Awad,E.J. Bolster,David Scott,Paramjit Kalirao,Pascal Dabel,Wesley B. Calhoun,Steven F. Gouge,Mark B. Warren,M. K. Lawrence,Aamir Jamal,Mohamed A. El-Shahawy,C. Mercado,Jayant Kumar,Pedro Velasquez-Mieyer,Robert Busch,Todd Lewis,Lisa Rich +211 more
TL;DR: Assessment of the blood pressure lowering efficacy of the dual endothelin antagonist aprocitentan in patients with resistant hypertension found it well tolerated and superior to placebo in lowering blood pressure at week 4 with a sustained effect at week 40.