Jay H. Kim
Duke University
12 Papers
243 Citations
Jay H. Kim is an academic researcher from Duke University. The author has contributed to research in topics: Intimal hyperplasia & Endothelium. The author has an hindex of 9, co-authored 12 publications. Previous affiliations of Jay H. Kim include University of Bergen & University of North Carolina at Chapel Hill.
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Papers
Experimental hypercholesterolemia in rabbits induces cavernosal atherosclerosis with endothelial and smooth muscle cell dysfunction.
Jay H. Kim,Michael L. Klyachkin,Einar Svendsen,Mark G. Davies,Per Otto Hagen,Culley C. Carson +5 more
TL;DR: Reduction of elevated serum cholesterol normalized cavernosal relaxation, including that of papaverine, and decreased the sensitivity to norepinephrine, thereby suggesting that cavernosal smooth muscle dysfunction in hypercholesterolemia is reversible.
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Investigative Urology: Modulation of Vasoactive Intestinal Polypeptide (VIP)-Mediated Relaxation by Nitric Oxide and Prostanoids in the Rabbit Corpus Cavernosum
TL;DR: It is suggested that VIP is a mediator of NANC cavernosal relaxation and that NO synthesis is involved in VIP-induced NANC relaxation in the corpus cavernosum.
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Hypercholesterolemia and Experimental Vein Grafts: Accelerated Development of Intimal Hyperplasia and an Increase in Abnormal Vasomotor Function
Michael L. Klyachkin,Mark G. Davies,Einar Svendsen,Jay H. Kim,Marga F. Massey,Lizzie Barber,Richard L. McCann,Per Otto Hagen +7 more
TL;DR: HC appears to induce intrinsic changes in smooth muscle cells which are linked to a greater proliferative and abnormal vasomotor capability and applications of vigorous anti-HC regimens perioperatively may be beneficial in maintaining patency over the longer term.
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Control of accelerated vein graft atheroma with the nitric oxide precursor: L-arginine.
TL;DR: L-arginine supplementation resulted in the preservation of acetylcholine-mediated relaxation but did not change hypercholesterolemia-induced contractile agonist supersensitivity.
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Modulation of vasoactive intestinal polypeptide (VIP)-mediated relaxation by nitric oxide and prostanoids in the rabbit corpus cavernosum.
TL;DR: In this paper, the polypeptide VIP has been shown to be an inhibitory nonadrenergic, noncholinergic (NANC) neurotransmitter involved in the relaxation of cavernosal smooth muscle during erection.
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