Jason R. Schmink
University of Pennsylvania
14 Papers
124 Citations
Jason R. Schmink is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Catalysis & Aryl. The author has an hindex of 7, co-authored 14 publications. Previous affiliations of Jason R. Schmink include University of Connecticut & Merck & Co..
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Papers
Reversed-Polarity Synthesis of Diaryl Ketones via Palladium-Catalyzed Cross-Coupling of Acylsilanes
Jason R. Schmink,Shane W. Krska +1 more
TL;DR: Scope and limitations of this novel method, using acylsilanes as acyl anion equivalents in a palladium-catalyzed cross-coupling reaction with aryl bromides to give unsymmetrical diaryl ketones, are presented.
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Pd-Catalyzed Aldehyde to Ester Conversion: A Hydrogen Transfer Approach
TL;DR: Aliphatic and aromatic aldehydes are successfully converted into their corresponding esters using Pd(OAc)(2) and XPhos using a hydrogen transfer protocol that mitigates the need for other oxidants.
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Fast, easy, solvent-free, microwave-promoted Michael addition of anilines to α,β-unsaturated alkenes: synthesis of N-aryl functionalized β-amino esters and acids
TL;DR: In this article, a microwave-promoted synthesis of N-aryl functionalized β-amino esters using Michael addition reactions is presented, where reactions are performed neat at 200 °C for 20 min and are catalyzed by acetic acid.
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Use of a scientific microwave apparatus for rapid optimization of reaction conditions in a monomode function and then substrate screening in a multimode function
TL;DR: In this article, the applicability of a monomode and a multimode microwave device for substrate screening in a multimodal environment is evaluated. But the authors focus on the effects of differences in microwave absorptivity of reaction mixtures on the product conversions in screening multiple substrates simultaneously in a multi-modal microwave apparatus.
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Palladium-catalyzed synthesis of diarylmethanes: exploitation of carbanionic leaving groups.
TL;DR: A novel route to the synthesis of diarylmethanes via a Pd-catalyzed alpha-arylation of benzyl ketones is reported, where the two phenyl rings of the intermediate are exploited to stabilize the high-energy carbanionic leaving group in a straightforward synthesis.
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