Jason P. Sheehan
University of Virginia
730 Papers
2.4K Citations
Jason P. Sheehan is an academic researcher from University of Virginia. The author has contributed to research in topics: Radiosurgery & Medicine. The author has an hindex of 67, co-authored 632 publications. Previous affiliations of Jason P. Sheehan include University of Texas Health Science Center at Houston & University of Virginia Health System.
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Papers
Dosimetric effects of Onyx embolization on Gamma Knife arteriovenous malformation dose distributions
TL;DR: Onyx embolization appears to have a detectable effect on the delivered dose distribution, however, the small changes in dose metrics and high Gamma passing rates at 1.0 mm tolerance suggest that these changes are unlikely to be clinically significant.
Gamma surgery in the treatment of nonsecretory pituitary macroadenoma
Vincenzo Mingione,Chun Po Yen,Mary Lee Vance,Melita Steiner,Jason P. Sheehan,Edward R. Laws,Ladislau Steiner +6 more
TL;DR: Current experience suggests that gamma surgery is an appropriate means of managing recurrent or residual nonsecretory pituitary macroadenoma following microsurgery and a primary treatment in selected patients.
Altered Calcium Homeostasis in Cells Transformed by Mitochondria from Individuals with Parkinson's Disease
Jason P. Sheehan,Russell H. Swerdlow,Parker Wd,Scott W. Miller,Robert E. Davis,Jeremy B. Tuttle +5 more
TL;DR: The subtle alteration in calcium homeostasis of Parkinson's disease cybrids may reflect an increased susceptibility to cell death under circumstances not ordinarily toxic.
Stereotactic Radiosurgery for Intracranial Noncavernous Sinus Benign Meningioma: International Stereotactic Radiosurgery Society Systematic Review, Meta-Analysis and Practice Guideline
Marcello Marchetti,Arjun Sahgal,Antonio A.F. De Salles,Marc Levivier,Marc Levivier,Lijun Ma,Ian Paddick,Bruce E. Pollock,Jean Régis,Jason P. Sheehan,John H. Suh,Shoji Yomo,Laura Fariselli +12 more
TL;DR: The current literature supporting SRS for benign intracranial meningioma lacks level I and II evidence, but when summarizing the large number of level III studies, it is clear that SRS can be recommended as an effective evidence-based treatment option (recommendation level II) for grade 1 menioma.
Preoperative stereotactic radiosurgery in the management of brain metastases and gliomas
Eric J. Lehrer,Roman O. Kowalchuk,Henry Ruiz-Garcia,Kenneth W. Merrell,D. D. Brown,Joshua D. Palmer,Stuart H. Burri,Jason P. Sheehan,Alfredo Quninoes-Hinojosa,Daniel M. Trifiletti +9 more
TL;DR: In addition to potentially permitting smaller target volumes, tissue analysis may permit characterization of DNA repair pathways and tumor microenvironment changes in response to SRS, which may be used to further tailor therapy and identify novel therapeutic targets.