Jarle Breivik
University of Oslo
38 Papers
672 Citations
Jarle Breivik is an academic researcher from University of Oslo. The author has contributed to research in topics: Mutation & Cancer. The author has an hindex of 19, co-authored 38 publications.
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Papers
Kirsten ras mutations in patients with colorectal cancer : the ‘RASCAL II’ study
H. J. N. Andreyev,A. R. Norman,David Cunningham,Jacqui Oates,B. R. Dix,Barry Iacopetta,J. Young,T. Walsh,Robyn L. Ward,Nicholas J. Hawkins,M. Beranek,P. Jandik,Robert Benamouzig,Eric Jullian,Pierre Laurent-Puig,Sylviane Olschwang,Oliver Müller,Ingrid Hoffmann,H. M. Rabes,C. Zietz,C. Troungos,C. Valavanis,S T Yuen,Jwc Ho,C. T. Croke,D. P. O'Donoghue,Walter Giaretti,A. Rapallo,Antonio Russo,Bazan,M. Tanaka,K. Omura,T. Azuma,Toshifumi Ohkusa,Takahiro Fujimori,Y. Ono,M. Pauly,C. Faber,R. Glaesener,A.F.P.M. de Goeij,Jan-Willem Arends,S. N. Andersen,T. Lovig,Jarle Breivik,Gustav Gaudernack,Ole Petter F. Clausen,P.M. De Angelis,Gunn Iren Meling,Torleiv O. Rognum,Richard Smith,H S Goh,A. Font,Rafael Rosell,Xiao-Feng Sun,Hong Zhang,J. Benhattar,L. Losi,J. Q Lee,Shan Tair Wang,Paul A. Clarke,Sandra M. Bell,Philip Quirke,Vivien J. Bubb,J. Piris,N. R. Cruickshank,Dion Morton,J. C. Fox,Fahd Al-Mulla,N. Lees,C. N. Hall,D. Snary,K. Wilkinson,Deborah A. Dillon,Jose Costa,V. E. Pricolo,S. D. Finkelstein,J. S. Thebo,Anthony J. Senagore,S. A. Halter,S. Wadler,S Malik,K. Krtolica,N. Urosevic +82 more
- 01 Sep 2001
TL;DR: It is suggested that not only is the presence of a codon 12 glycine to valine mutation important for cancer progression but also that it may predispose to more aggressive biological behaviour in patients with advanced colorectal cancer.
204
Different genetic pathways to proximal and distal colorectal cancer influenced by sex-related factors.
Jarle Breivik,Ragnhild A. Lothe,Gunn Iren Meling,Torleiv O. Rognum,Anne Lise Børresen-Dale,Gustav Gaudernack +5 more
TL;DR: It is confirmed that different genetic pathways to colorectal cancer dominate in the proximal and distal segments of the bowel and suggest that the K‐ras‐ and MIN‐dependent pathways are influenced by different sex‐related factors.
191
The evolutionary origin of genetic instability in cancer development
TL;DR: This paper addresses the problem of applying the concept of clonal selection to genetically unstable cells and presents an alternative perspective based on the principles of molecular evolution that explains genetic instability in terms of competition between genetic strategies and draws lines to basic aspects of evolutionary biology.
108
Evaluation of the medical student research programme in Norwegian medical schools. A survey of students and supervisors
Steinar Hunskaar,Jarle Breivik,Maje Siebke,Karin Tømmerås,Kristian Figenschau,John-Bjarne Hansen +5 more
TL;DR: The Medical Student Research Programme has led to an increase in the recruitment of graduated physicians to medical research in Norway, and it will only be possible to evaluate whether this in turn will result in a larger number of PhDs in 3–5 years; this will also depend on the access to grants and fellowships.
p21‐ras‐peptide‐specific T‐cell responses in a patient with colorectal cancer. CD4+ and CD8+ T cells recognize a peptide corresponding to a common mutation (13Gly → Asp)
Beate Fossum,Tobias Gedde-Dahl,Jarle Breivik,Jon Amund Eriksen,Anne Spurkland,Erik Thorsby,Gustav Gaudernack +6 more
TL;DR: This study demonstrates a mutant ras‐specific T‐cell response of both the CD4+ and the CD8+ phenotype in a cancer patient, and speculate that in this patient a specific T‐ cell response resulted in eradication of tumor cells harboring the 13Gly → Asp mutation.
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