Jaring Schreuder
Walter and Eliza Hall Institute of Medical Research
15 Papers
13 Citations
Jaring Schreuder is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Haematopoiesis & Progenitor cell. The author has an hindex of 7, co-authored 12 publications. Previous affiliations of Jaring Schreuder include University of Queensland & University of Melbourne.
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Papers
Identification of cDC1- and cDC2-committed DC progenitors reveals early lineage priming at the common DC progenitor stage in the bone marrow
Andreas Schlitzer,V. Sivakamasundari,Jinmiao Chen,Hermi Sumatoh,Jaring Schreuder,Josephine Lum,Benoit Malleret,Sanqian Zhang,Anis Larbi,Francesca Zolezzi,Laurent Rénia,Michael Poidinger,Shalin H. Naik,Evan W. Newell,Paul Robson,Florent Ginhoux +15 more
TL;DR: This work found that transcriptional signatures of the cDC1 and cDC2 lineages became evident at the single-cell level from the CDP stage, and identified Siglec-H and Ly6C as lineage markers that distinguished pre-DC subpopulations committed to the c DC1 lineage (SigleC-H−Ly6C− pre- DCs) or c DC2 lineage (CDC2 lineage).
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Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells
TL;DR: As shown using clonal assays, the mouse HSC population undergoes quantitative as well as qualitative changes with age, including lineage differentiation, HSC pool size, marrow-homing efficiency, and self-renewal.
Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer.
Delphine Merino,Tom S. Weber,Tom S. Weber,Antonin Serrano,Antonin Serrano,François Vaillant,François Vaillant,Kevin H. Liu,Kevin H. Liu,Bhupinder Pal,Bhupinder Pal,L Di Stefano,Jaring Schreuder,Jaring Schreuder,Dawn S. Lin,Dawn S. Lin,Yunshun Chen,Yunshun Chen,Marie Liesse Asselin-Labat,Marie Liesse Asselin-Labat,Ton N. Schumacher,Daniel L Cameron,Gordon K. Smyth,Gordon K. Smyth,Anthony T. Papenfuss,Geoffrey J. Lindeman,Jane E. Visvader,Jane E. Visvader,Shalin H. Naik,Shalin H. Naik +29 more
TL;DR: In this article, cellular barcoding of two treatment-naive TNBC patient-derived xenografts (PDXs) was used to track the spatio-temporal fate of thousands of barcoded clones in primary tumors, and their metastases.
Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma
Nicolas Jacquelot,Nicolas Jacquelot,Nicolas Jacquelot,Cyril Seillet,Cyril Seillet,Minyu Wang,Minyu Wang,Angela Pizzolla,Angela Pizzolla,Yang Liao,Soroor Hediyeh-Zadeh,Soroor Hediyeh-Zadeh,Sharon Grisaru-Tal,Cynthia Louis,Cynthia Louis,Qiutong Huang,Qiutong Huang,Qiutong Huang,Jaring Schreuder,Fernando Souza-Fonseca-Guimaraes,Carolyn A. de Graaf,Carolyn A. de Graaf,Kevin Y. T. Thia,Sean Macdonald,Mary J Camilleri,Mary J Camilleri,Kylie Luong,Kylie Luong,Shengbo Zhang,Shengbo Zhang,Michael Chopin,Michael Chopin,Tristan Molden-Hauer,Stephen L. Nutt,Stephen L. Nutt,Viktor Umansky,Viktor Umansky,Bogoljub Ciric,Joanna R Groom,Joanna R Groom,Paul S. Foster,Philip M. Hansbro,Philip M. Hansbro,Philip M. Hansbro,Andrew N. J. McKenzie,Daniel H.D. Gray,Daniel H.D. Gray,Andreas Behren,Andreas Behren,Jonathan Cebon,Eric Vivier,Ian P. Wicks,Ian P. Wicks,Ian P. Wicks,Joseph A. Trapani,Joseph A. Trapani,Ariel Munitz,Melissa J. Davis,Melissa J. Davis,Wei Shi,Paul J Neeson,Paul J Neeson,Gabrielle T. Belz,Gabrielle T. Belz,Gabrielle T. Belz +64 more
TL;DR: This paper found that high ILC2 infiltration in human melanoma was associated with a good clinical prognosis and revealed a potential synergistic approach to harness group 2 innate lymphoid cells for antitumor immunotherapies.
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Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT.
Michael Chopin,Michael Chopin,Aaron T. L. Lun,Aaron T. L. Lun,Yifan Zhan,Yifan Zhan,Jaring Schreuder,Jaring Schreuder,Hannah D. Coughlan,Hannah D. Coughlan,Angela D'Amico,Angela D'Amico,Lisa A. Mielke,Lisa A. Mielke,Lisa A. Mielke,Francisca F. Almeida,Francisca F. Almeida,Andrew J. Kueh,Andrew J. Kueh,Ross A. Dickins,Gabrielle T. Belz,Gabrielle T. Belz,Shalin H. Naik,Shalin H. Naik,Andrew M. Lew,Andrew M. Lew,Phillipe Bouillet,Phillipe Bouillet,Marco J Herold,Marco J Herold,Gordon K. Smyth,Gordon K. Smyth,Lynn M. Corcoran,Lynn M. Corcoran,Stephen L. Nutt,Stephen L. Nutt +35 more
TL;DR: It is found that conditional ablation of the Ets‐family transcription factor PU.1 in DC‐restricted progenitors led to increased pDC production at the expense of cDCs, and a key role in maintaining cDC identity through the induction of the transcriptional regulator DC‐SCRIPT is revealed.
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