Jannik Traut
4 Papers
Jannik Traut is an academic researcher. The author has contributed to research in topics: MDA5 & Innate immune system. The author has co-authored 1 publications.
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Papers
Comparison of HAV and HCV infections in vivo and in vitro reveals distinct patterns of innate immune evasion and activation
Ombretta Colasanti,Rani Burm,Hao En Huang,Tobias Riedl,Jannik Traut,Nadine Gillich,Teng-Feng Li,Laura Corneillie,Suzanne Faure-Dupuy,Oliver Grünvogel,Danijela Heide,Ji-Young Lee,Cong Si Tran,Uta Merle,Maria Chironna,Florian W. R. Vondran,Katharina Esser-Nobis,Marco Binder,Ralf Bartenschlager,Mathias F. Heikenwälder,Philip Meuleman,Volker Lohmann +21 more
TL;DR: In this article, the authors investigated the mechanisms of HAV and hepatitis C virus (HCV) induction and counteraction by HAV proteases in vivo and in vitro and found that HAV 3ABC and 3CD proteases do not abolish the host innate immune response.
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RBM39 shapes innate immunity through transcriptional and splicing control of IRF3 and other key factors
Teng-Feng Li,Arthur Lang,Paul Rothhaar,Oliver Grünvogel,Ombretta Colasanti,Santa Mariela Olivera Ugarte,Jannik Traut,Antonio Piras,Nelson Acosta-Rivero,Vladimir Gonçalves Magalhães,Emely Springer,Andreas Betz,Jeongbin Park,Ruiyue Qiu,Gnimah Eva Gnouamozi,Ann-Kathrin Mehnert,Viet Loan Dao Thi,Stephan Urban,Martina Muckenthaler,Matthias Schlesner,Dirk Wohlleber,Marco Binder,R. Bartenschlager,Andreas Pichlmair,Volker Lohmann +24 more
TL;DR: RBM39 acts as a novel innate immune factor by regulating transcription and/or alternative splicing of IRF3 and several other key proteins involved in innate immune responses.
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RBM39 shapes innate immunity by controlling the expression of key factors of the interferon response
Teng-Feng Li,Paul Rothhaar,Arthur Lang,Oliver Grünvogel,Ombretta Colasanti,Santa Mariela Olivera Ugarte,Jannik Traut,Antonio Piras,Nelson Acosta-Rivero,Vladimir Gonçalves Magalhães,Emely Springer,Andreas Betz,Hao-En Huang,Jeongbin Park,Ruiyue Qiu,Gnimah Eva Gnouamozi,Ann-Kathrin Mehnert,Viet Loan Dao Thi,Stephan Urban,Martina U Muckenthaler,M. Schlesner,Dirk Wohlleber,Marco Binder,Ralf Bartenschlager,Andreas Pichlmair,Volker Lohmann +25 more
Corrigendum to "Comparison of HAV and HCV infections in vivo and in vitro reveals distinct patterns of innate immune evasion and activation" [J Hepatol (2023) 645-656].
Ombretta Colasanti,Rani Burm,Hao-En Huang,Tobias Riedl,Jannik Traut,Nadine Gillich,Teng-Feng Li,Laura Corneillie,Suzanne Faure-Dupuy,Oliver Grünvogel,Danijela Heide,Ji-Young Lee,Cong Si Tran,Uta Merle,Maria Chironna,Florian F W Vondran,Katharina Esser-Nobis,Marco Binder,Ralf Bartenschlager,Mathias Heikenwälder,Philip Meuleman,Volker Lohmann +21 more
TL;DR: A corrigendum corrects an error in Fig. 4G of a study comparing HAV and HCV infections, where HAV's 3ABC protein size was mislabelled as 75 kDa instead of 38 kDa, affecting understanding of immune evasion mechanisms.