Janine Liburd
Queen's University
3 Papers
17 Citations
Janine Liburd is an academic researcher from Queen's University. The author has contributed to research in topics: Myosin light-chain kinase & Calmodulin. The author has an hindex of 3, co-authored 3 publications.
Chat about Author
Papers
Identification of calmodulin and MlcC as light chains for Dictyostelium myosin-I isozymes.
TL;DR: Each long-tailed Dictyostelium myosin-I has now been shown to have a unique light chain, whereas the short-tailed myosins-I, MyoA and MyoE, have the multifunctional calmodulin as a light chain.
14
Structure of the Single-lobe Myosin Light Chain C in Complex with the Light Chain-binding Domains of Myosin-1C Provides Insights into Divergent IQ Motif Recognition
David N. Langelaan,Janine Liburd,Yidai Yang,Emily Miller,Seth Chitayat,Scott W. Crawley,Graham P. Côté,Steven P. Smith +7 more
TL;DR: The N- and C-terminal regions of MlcC make critical contacts that contribute to its specific interactions with the myosin-1C divergent IQ motifs, which are contacts that deviate from the traditional mode of calmodulin-IQ recognition.
11
Structure of the small Dictyostelium discoideum myosin light chain MlcB provides insights into MyoB IQ motif recognition.
Janine Liburd,Seth Chitayat,Scott W. Crawley,Kim Munro,Emily Happy Miller,Chris M. Denis,Holly L. Spencer,Graham P. Côté,Steven P. Smith +8 more
TL;DR: It is concluded that the mode of IQ motif recognition by the novel single-lobe MlcB differs considerably from that of stereotypical bilobal light chains such as calmodulin.
5