Jane E. Tully
University of Vermont
10 Papers
25 Citations
Jane E. Tully is an academic researcher from University of Vermont. The author has contributed to research in topics: Proinflammatory cytokine & Inflammation. The author has an hindex of 10, co-authored 10 publications.
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Papers
Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosis
Sidra M. Hoffman,Jane E. Tully,James D. Nolin,Karolyn G. Lahue,Dylan Goldman,Nirav Daphtary,Minara Aliyeva,Charles G. Irvin,Anne E. Dixon,Matthew E. Poynter,Vikas Anathy +10 more
TL;DR: It is indicated that HDM induces ER stress in airway epithelial cells and that ATF6α and ERp57 play a significant role in the development of cardinal features of allergic airways disease.
Epithelial NF-κB Orchestrates House Dust Mite–Induced Airway Inflammation, Hyperresponsiveness, and Fibrotic Remodeling
Jane E. Tully,Sidra M. Hoffman,Karolyn G. Lahue,James D. Nolin,Vikas Anathy,Lennart K. A. Lundblad,Nirav Daphtary,Minara Aliyeva,Kendall E. Black,Anne E. Dixon,Matthew E. Poynter,Charles G. Irvin,Yvonne M. W. Janssen-Heininger +12 more
TL;DR: It is demonstrated that following airway exposure with an asthma-relevant allergen, activation of classical and alternative NF-κB pathways occurs within the airway epithelium and may coordinately contribute to allergic inflammation, AHR, and fibrotic airway remodeling.
77
Activation of the glutaredoxin-1 gene by nuclear factor κB enhances signaling
Scott W. Aesif,Ine Kuipers,Jos van der Velden,Jane E. Tully,Amy S. Guala,Vikas Anathy,Juliana I. Sheely,Niki L. Reynaert,Emiel F.M. Wouters,Albert van der Vliet,Yvonne M. W. Janssen-Heininger +10 more
TL;DR: It is demonstrated that the Glrx1 gene is positively regulated by NF-κB and a feed-forward mechanism to promote NF-σκB signaling by decreasing S-glutathionylation is suggested.
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Emerging mechanisms of glutathione-dependent chemistry in biology and disease.
Yvonne M. W. Janssen-Heininger,James D. Nolin,Sidra M. Hoffman,Jos van der Velden,Jane E. Tully,Karolyn G. Lahue,Sarah Abdalla,David G. Chapman,Niki L. Reynaert,Albert van der Vliet,Vikas Anathy +10 more
TL;DR: This perspective offers a concise overview of the emerging field of protein thiol redox modifications through covalent modification to reactive cysteines within proteins, a process known as S‐glutathionylation.
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Cooperation between Classical and Alternative NF-κB Pathways Regulates Proinflammatory Responses in Epithelial Cells
Jane E. Tully,James D. Nolin,Amy S. Guala,Sidra M. Hoffman,Elle C. Roberson,Karolyn G. Lahue,Jos van der Velden,Vikas Anathy,Timothy S. Blackwell,Yvonne M. W. Janssen-Heininger +9 more
TL;DR: Results demonstrate that the coordinated activation of both NF-κB pathways regulates the magnitude and nature of proinflammatory responses in lung epithelial cells.