Janalee Isaacson
University of Missouri–Kansas City
6 Papers
2 Citations
Janalee Isaacson is an academic researcher from University of Missouri–Kansas City. The author has contributed to research in topics: Jatropha curcas & Bone remodeling. The author has an hindex of 3, co-authored 6 publications. Previous affiliations of Janalee Isaacson include Johnson County Community College.
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Papers
Jatropha curcas: from biodiesel generation to medicinal applications.
Luis Cesar Maffei Sartini Paulillo,Chenglin Mo,Janalee Isaacson,Luciene Lessa,Edjacy Lopes,Sandra Romero-Suarez,Leticia Brotto,Eduardo Abreu,William G. Gutheil,Marco Brotto +9 more
TL;DR: A series of pilot studies are performed that demonstrate that JC is able to protect skeletal muscle cells in vitro against the deleterious effects of ethanol, and it is determined that JC's effects are mediated by the up regulation of HSP60, a critical mitochondrial heat shock related protein that is essential for intracellular REDOX regulation.
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PinhãO-Manso: A Native Jatropha Curcas from Brazil Protects Muscle Cells from Ethanol Toxicity and Improves Muscle Function
Leticia Brotto,Luis Cesar Maffei Sartini Paulillo,Edjacy Lopes,Chenglin Mo,Janalee Isaacson,Pedro Carneiro,Luciene Lessa,Sandra Romero-Suarez,Eduardo Abreu,Marco Brotto +9 more
TL;DR: The studies indicate that native Jatropha curcas from Salvador, Brazil could have potential applications for improvement of skeletal muscle function and purification of active principle(s) of PM that might underlie its potent and beneficial effects on muscle function are indicated.
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Extracellular Membrane Vesicles Derived from 143B Osteosarcoma Cells Contain Pro-Osteoclastogenic Cargo: A Novel Communication Mechanism in Osteosarcoma Bone Microenvironment.
Rama Garimella,Laurie Washington,Janalee Isaacson,Julian Vallejo,Madoka Spence,Ossama Tawfik,Peter S. N. Rowe,Marco Brotto,Raymond P. Perez +8 more
TL;DR: It is demonstrated that 143B osteosarcoma cells generate EMVs mainly by mechanisms involving increased intracellular calcium or cAMP levels, and contain pro-osteoclastic cargo.
The Muscle-Bone Connection
Marco Brotto,Janalee Isaacson,Eduardo Abreu +2 more
- 01 Jan 2016
TL;DR: The endocrine nature of bones and skeletal muscles has become evident with the identification of several secreted molecules from these tissues, and large bivariate GWAS studies that have identified potentially pleiotropic bone-muscle genes justifies a closer examination of the biochemical crosstalk between bones and muscles.