Jan M. Warnking
Montreal Neurological Institute and Hospital
6 Papers
18 Citations
Jan M. Warnking is an academic researcher from Montreal Neurological Institute and Hospital. The author has contributed to research in topics: Cerebral blood flow & Chemistry. The author has an hindex of 5, co-authored 6 publications.
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Papers
Hemodynamic and metabolic responses to neuronal inhibition.
TL;DR: The findings characterize the hemodynamic and metabolic downregulation accompanying neuronal inhibition and thereby establish the sustained negative BOLD response as a marker of neuronal deactivation.
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Hemodynamic and metabolic responses to activation, deactivation and epileptic discharges.
Bojana Stefanovic,Jan M. Warnking,Eliane Kobayashi,Andrew P. Bagshaw,Colin Hawco,François Dubeau,Jean Gotman,G. Bruce Pike +7 more
TL;DR: Evidence is provided for a preserved coupling between hemodynamic and metabolic changes in response to both functional activation and, for the two case studies available, in Response to interictal epileptiform activity.
126
Reducing contamination while closing the gap: BASSI RF pulses in PASL.
Jan M. Warnking,G. Bruce Pike +1 more
TL;DR: In an in vivo study on four subjects, contamination effects in a QUIPSS II PASL implementation based on BASSI pulses are compared to those present in a state‐of‐the‐art Q2TIPS sequence employing a FOCI label pulse.
18
Dependence of the hemodynamic response to functional activation on the CO2-induced vasodilation
TL;DR: A significant drop of activation-induced BOLD response magnitude with increasing basal flow levels is observed, in accordance with the BOLD responded models, whereby a significant drop in the basal deoxyhemoglobin concentration decreases its sensitivity to CBF increases.
Bandwidth-modulated adiabatic RF pulses for uniform selective saturation and inversion.
Jan M. Warnking,G. Bruce Pike +1 more
TL;DR: BASSI RF pulses are compared to existing gradient modulated adiabatic pulses in simulations and phantom experiments and shown to be superior in terms of selectivity and homogeneity, while requiring less RF energy.