Jan E. Greving
University of Groningen
6 Papers
95 Citations
Jan E. Greving is an academic researcher from University of Groningen. The author has contributed to research in topics: Gas chromatography & Derivatization. The author has an hindex of 6, co-authored 6 publications.
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Papers
Determination of carboxylic acids in the picomole range after derivatization with pentafluorobenzyl bromide and electron capture gas chromatography
TL;DR: In this paper, a method for the determination of picomole quantities of carboxylic acids by gas chromatography in combination with electron capture detection is presented, where the acids are extracted from aqueous media into dichloromethane by ion-pair extraction with tetrapentylammonium ions, and derivatized as their pentafluorobenzyl esters.
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Analysis of quaternary ammonium-compounds and basic drugs based on ion-pair adsorption high-performance liquid-chromatography
TL;DR: In this paper, a general approach to the ion-pair adsorption high-performance liquid chromatography of basic drugs and quaternary ammonium compounds is decribed in which suitable counter ions such as Br− and ClO4− are dissolved in the eluent.
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Ion-pair adsorption chromtography of basic drugs using straight-phase systems on silica gel thin layers
TL;DR: A general approach to the ion-pair adsoption chromatography of basic drugs on silica gel thin layers is described in this paper, where the authors show that basic drugs will migrate as uncharged ion pairs if a suitable inoraganic counter ion such as Br − or Cl − is present in sufficient amounts.
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Determination of oxyphenonium bromide in plasma and urine by means of ion-pair extraction, derivatization and gas chromatography-electron-capture detection
TL;DR: A sensitive and selective method for the determination of the quaternary ammonium compound oxyphenonium bromide (Antrenyl), a drug with strong anticholinergic properties, in human plasma and urine is described.
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Identification of Ergot-peptide alkaloids, based on gas—liquid chromatography of the peptide moiety
TL;DR: In this paper, a simple and rapid method for the identification of ergot-peptide alkaloids is described, where at temperatures around 300° instantaneous degrations of the free alkaloid occurs in the injection port of the gas chromatograph, each peptide yielding a specific set of peptide degradation products, which are subsequently separated on a SE-30 column.
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