Jan Barciszewski
Polish Academy of Sciences
46 Papers
172 Citations
Jan Barciszewski is an academic researcher from Polish Academy of Sciences. The author has contributed to research in topics: RNA & Glioma. The author has an hindex of 17, co-authored 46 publications. Previous affiliations of Jan Barciszewski include Adam Mickiewicz University in Poznań.
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Papers
Let food be your medicine: nutraceutical properties of lycopene.
Małgorzata Grabowska,Dariusz Wawrzyniak,Katarzyna Rolle,Katarzyna Rolle,Piotr Chomczyński,Stefan Oziewicz,Stefan Jurga,Jan Barciszewski,Jan Barciszewski +8 more
TL;DR: Lycopene has the greatest antioxidant potential among carotenoids and can function as a proper causative treatment of disease, according to primary research and clinical trials involving lycopene.
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The reverse-transcriptase/RNA-maturase protein MatR is required for the splicing of various group II introns in Brassicaceae mitochondria
Laure D. Sultan,Daria Mileshina,Felix Grewe,Katarzyna Rolle,Sivan Abudraham,Paweł Głodowicz,Adnan Khan Niazi,Ido Keren,Sofia Shevtsov,Liron Klipcan,Jan Barciszewski,Jeffrey P. Mower,André Dietrich,Oren Ostersetzer-Biran +13 more
TL;DR: Directed knockdown of matR expression via synthetically designed ribozymes altered the processing of various introns, including nad1 i4, suggesting that MatR may represent an intermediate link in the gradual evolutionary transition from the intron-specific maturases in bacteria into their versatile spliceosomal descendants in the nucleus.
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Mature MiRNAs Form Secondary Structure, which Suggests Their Function beyond RISC
Agnieszka Belter,Dorota Gudanis,Katarzyna Rolle,Monika Piwecka,Zofia Gdaniec,Mirosława Z. Naskręt-Barciszewska,Jan Barciszewski +6 more
TL;DR: The structural similarity of these miRNA hairpins and anti-Tn-C aptamers indicates that miRNAs may function also beyond RISC and are even more sophisticated regulators, that it was previously expected.
The Sequence and Structure Determine the Function of Mature Human miRNAs.
Katarzyna Rolle,Monika Piwecka,Agnieszka Belter,Dariusz Wawrzyniak,Jaroslaw Jeleniewicz,Miroslawa Z. Barciszewska,Jan Barciszewski +6 more
TL;DR: It is found that the specific group of miRNAs with UGUGU can activate the targets associated to the interferon induction pathway or pathways prominently observed during carcinogenesis.
Promising human brain tumors therapy with interference RNA intervention (iRNAi)
Katarzyna Rolle,Stanisław Nowak,Eliza Wyszko,Monika Nowak,Zukiel R,Rafal Piestrzeniewicz,Iwona Gawronska,Miroslawa Z. Barciszewska,Jan Barciszewski +8 more
TL;DR: A novel strategy for human brain tumors therapy based on RNA interference (RNAi) and its application after surgery (intervention with RNAi) to inhibit TN-C synthesis is described, which is the first protocol of RNAi application in human brain tumor treatment.
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