Jamie Dean
The Royal Marsden NHS Foundation Trust
23 Papers
54 Citations
Jamie Dean is an academic researcher from The Royal Marsden NHS Foundation Trust. The author has contributed to research in topics: Medicine & Mucositis. The author has an hindex of 11, co-authored 19 publications. Previous affiliations of Jamie Dean include Institute of Cancer Research & Harvard University.
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Papers
Normal tissue complication probability (NTCP) modelling using spatial dose metrics and machine learning methods for severe acute oral mucositis resulting from head and neck radiotherapy.
Jamie Dean,Kee H. Wong,Liam Welsh,Ann-Britt Jones,Ulrike Schick,Kate Newbold,Shreerang Bhide,Shreerang Bhide,Kevin J. Harrington,Kevin J. Harrington,Christopher M. Nutting,Christopher M. Nutting,Sarah L. Gulliford +12 more
TL;DR: The RFCstandard model performance is modest-to-good, but should be improved, and requires external validation, while reducing the volumes of oral cavity receiving intermediate and high doses may reduce mucositis incidence.
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Neurocognitive Function After (Chemo)-Radiotherapy for Head and Neck Cancer
Liam Welsh,Alex Dunlop,T. McGovern,D. McQuaid,Jamie Dean,Sarah L. Gulliford,S.A. Bhide,S.A. Bhide,Kevin J. Harrington,Kevin J. Harrington,Christopher M. Nutting,Katie L. Newbold +11 more
TL;DR: Evidence relating to the late neurotoxicity of radical (chemo)-radiotherapy for HNC is reviewed, with a focus on studies of NCF in this patient population.
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A randomised assessment of image guided radiotherapy within a phase 3 trial of conventional or hypofractionated high dose intensity modulated radiotherapy for prostate cancer.
Julia Murray,Clare Griffin,Sarah L. Gulliford,Isabel Syndikus,John Staffurth,Miguel Panades,Christopher D Scrase,Chris Parker,Vincent Khoo,Jamie Dean,Helen Mayles,P. Mayles,Simon Thomas,O. Naismith,A. Baker,Helen Mossop,Clare Cruickshank,Emma Hall,David P. Dearnaley +18 more
TL;DR: In conclusion, introduction of daily online prostate IGRT was feasible in a national randomised trial and Dosimetric benefits seen in patients treated with I GRT and reduced CTV-PTV margins were seen.
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Incorporating spatial dose metrics in machine learning-based normal tissue complication probability (NTCP) models of severe acute dysphagia resulting from head and neck radiotherapy
Jamie Dean,Kee Wong,Liam Welsh,Ann-Britt Jones,Ulricke Schick,Jung Hun Oh,Aditya Apte,Kate Newbold,Kate Newbold,Shreerang Bhide,Shreerang Bhide,Kevin J. Harrington,Kevin J. Harrington,Joseph O. Deasy,Christopher M. Nutting,Christopher M. Nutting,Sarah L. Gulliford +16 more
TL;DR: Doses of approximately 1 Gy/fraction were most strongly associated with severe dysphagia and no spatial variation in radiosensitivity was observed for the pharyngeal mucosa.
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Spatial intra-tumor heterogeneity is associated with survival of lung adenocarcinoma patients
Hua-Jun Wu,Daniel Temko,Zoltan Maliga,Andre L. Moreira,Emi Sei,Darlan Conterno Minussi,Jamie Dean,Charlotte E. Lee,Qiong-Li Xu,Guillaume Hochart,Connor A. Jacobson,Clarence Yapp,Denis Schapiro,Peter K. Sorger,Erin H. Seeley,Nicholas Navin,Robert J. Downey,Franziska Michor +17 more
TL;DR: In this article , the authors presented a comprehensive spatial mapping of intra-tumor heterogeneity in lung adenocarcinoma and provided insights into the mechanisms and clinical consequences of GD.
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