James Wilson
Institute for Systems Biology
4 Papers
4 Citations
James Wilson is an academic researcher from Institute for Systems Biology. The author has contributed to research in topics: Biology & Gene. The author has an hindex of 1, co-authored 2 publications.
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Papers
Synergistic epistasis enhances the co-operativity of mutualistic interspecies interactions.
Serdar Turkarslan,Nejc Stopnisek,Anne W. Thompson,Christina E. Arens,Jacob J. Valenzuela,James Wilson,Kristopher A. Hunt,Jessica Hardwicke,Adrián López García de Lomana,Sujung Lim,Yee Mey Seah,Ying Fu,Liyou Wu,Jizhong Zhou,Kristina L. Hillesland,David A. Stahl,Nitin S. Baliga +16 more
TL;DR: In this article, the authors investigate whether early mutations improve cooperativity by manifesting in synergistic epistasis between genomes of the mutually interacting species, and demonstrate that cooperativity of a mutualism can improve through synergy between genomes.
Synergistic epistasis enhances cooperativity of mutualistic interspecies interactions
Serdar Turkarslan,Nejc Stopnisek,Anne W. Thompson,Christina E. Arens,Jacob J. Valenzuela,James Wilson,Kristopher A. Hunt,Jessica Hardwicke,Sujung Lim,Yee Mey Seah,Ying Fu,Liyou Wu,Jizhong Zhou,Kristina L. Hillesland,David A. Stahl,Nitin S. Baliga +15 more
TL;DR: An in-depth investigation revealed that synergistic epistasis across Dv and Mm genotypes had enhanced cooperativity within SR- and SR+ assemblages, allowing their co-existence as r- and K-strategists, respectively.
Origin of biogeographically distinct ecotypes during laboratory evolution
Jacob J. Valenzuela,Selva Rupa Christinal Immanuel,James Wilson,Serdar Turkarslan,Maryann K Ruiz,Sean M. Gibbons,Kristopher A. Hunt,Manfred Auer,Marcin Zemla,David A. Stahl,Nitin S. Baliga +10 more
TL;DR: In this article , the authors show how a handful of mutations that arise in one environmental context can drive resource partitioning by ecologically differentiated variants in another environmental context, whose interplay synergistically improves productivity of the entire mutualistic community.
Growth phase estimation for abundant bacterial populations sampled longitudinally from human stool metagenomes
Joe Jongpyo Lim,Christian Diener,James Wilson,Jacob J. Valenzuela,Nitin S. Baliga,Sean M. Gibbons +5 more
TL;DR: In this article , the authors proposed a model of the human gut as a flow-through ecosystem at a dynamical steady state, where population dynamics occur internally and the bacterial population sizes measured in a bolus of stool represent an endpoint of these internal dynamics.